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aspartate-semialdehyde dehydrogenase [Enterovibrio norvegicus].


LOCUS       WP_017005821             341 aa            linear   BCT 29-NOV-2019
ACCESSION   WP_017005821
VERSION     WP_017005821.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 341)
  AUTHORS   Nichols,C.E., Dhaliwal,B., Lockyer,M., Hawkins,A.R. and
            Stammers,D.K.
  TITLE     High-resolution structures reveal details of domain closure and
            'half-of-sites-reactivity' in Escherichia coli aspartate
            beta-semialdehyde dehydrogenase
  JOURNAL   J. Mol. Biol. 341 (3), 797-806 (2004)
   PUBMED   15288787
REFERENCE   2  (residues 1 to 341)
  AUTHORS   Blanco,J., Moore,R.A., Kabaleeswaran,V. and Viola,R.E.
  TITLE     A structural basis for the mechanism of aspartate-beta-semialdehyde
            dehydrogenase from Vibrio cholerae
  JOURNAL   Protein Sci. 12 (1), 27-33 (2003)
   PUBMED   12493825
REFERENCE   3  (residues 1 to 341)
  AUTHORS   Moore,R.A., Bocik,W.E. and Viola,R.E.
  TITLE     Expression and purification of aspartate beta-semialdehyde
            dehydrogenase from infectious microorganisms
  JOURNAL   Protein Expr. Purif. 25 (1), 189-194 (2002)
   PUBMED   12071715
REFERENCE   4  (residues 1 to 341)
  AUTHORS   Le,Y., He,J. and Vining,L.C.
  TITLE     Streptomyces akiyoshiensis differs from other gram-positive
            bacteria in the organization of a core biosynthetic pathway gene
            for aspartate family amino acids
  JOURNAL   Microbiology (Reading, Engl.) 142 (Pt 4), 791-798 (1996)
   PUBMED   8936306
REFERENCE   5  (residues 1 to 341)
  AUTHORS   Raczynska-Pawelec,A., Pawelec,D., Rozynek,E. and
            Jagusztyn-Krynicka,E.K.
  TITLE     Characterization of Campylobacter jejuni asd gene cloned in
            Escherichia coli
  JOURNAL   Acta Microbiol. Pol. 44 (3-4), 227-241 (1995)
   PUBMED   8934665
REFERENCE   6  (residues 1 to 341)
  AUTHORS   Cirillo,J.D., Weisbrod,T.R., Pascopella,L., Bloom,B.R. and
            Jacobs,W.R. Jr.
  TITLE     Isolation and characterization of the aspartokinase and aspartate
            semialdehyde dehydrogenase operon from mycobacteria
  JOURNAL   Mol. Microbiol. 11 (4), 629-639 (1994)
   PUBMED   7910936
REFERENCE   7  (residues 1 to 341)
  AUTHORS   Follettie,M.T., Peoples,O.P., Agoropoulou,C. and Sinskey,A.J.
  TITLE     Gene structure and expression of the Corynebacterium flavum N13
            ask-asd operon
  JOURNAL   J. Bacteriol. 175 (13), 4096-4103 (1993)
   PUBMED   8100567
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF011456.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK14874
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     Protein         1..341
                     /product="aspartate-semialdehyde dehydrogenase"
                     /EC_number="1.2.1.11"
                     /GO_function="GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008652 - cellular amino acid biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=37723
     Region          9..339
                     /region_name="Asd"
                     /note="Aspartate-semialdehyde dehydrogenase [Amino acid
                     transport and metabolism]; COG0136"
                     /db_xref="CDD:439906"
ORIGIN      
        1 mtqefdvafd iavlgatgav grtiievleq rkfpvrnlyl lasersaget irfngksilv
       61 kdvedfdwsq vqlalfsaga elsdrwapia ahegvvvidn tsrfryehdv plvvpevnpe
      121 aiadfrnrni ianpncstiq mlvalkpiyd vagierinva tyqsvsgsgk kgvdelagqt
      181 vrllnsqeae pslyktqiaf nclphidefm dngytkeemk mvwetqkilg ddtvavnptc
      241 vrvpvfygha eavhiecrqp idateamdll sraesvqvfm gedyptqvke gtgqdhvmvg
      301 rvrndishpn glnmwivadn vrkgaatnsv qiaevlirdy l