MULTISPECIES: carbonate dehydratase [Enterovibrio].

LOCUS       WP_017005483             216 aa            linear   BCT 28-AUG-2024
ACCESSION   WP_017005483
VERSION     WP_017005483.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio
  ORGANISM  Enterovibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 216)
  AUTHORS   Langereis,J.D., Zomer,A., Stunnenberg,H.G., Burghout,P. and
            Hermans,P.W.
  TITLE     Nontypeable Haemophilus influenzae carbonic anhydrase is important
            for environmental and intracellular survival
  JOURNAL   J Bacteriol 195 (12), 2737-2746 (2013)
   PUBMED   23564172
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007756.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10437
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..216
                     /organism="Enterovibrio"
                     /db_xref="taxon:188143"
     gene            1..216
                     /gene="can"
     Protein         1..216
                     /product="carbonate dehydratase"
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /calculated_mol_wt=24320
     Region          1..215
                     /region_name="beta_CA"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; cl00391"
                     /db_xref="CDD:469755"
     Site            order(33,35,42,44..46,58,61,83,88,98,101,181)
                     /site_type="active"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238448"
     Site            order(42,44,98,101)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238448"
     Site            order(43..46,48,50..51,53,58..60,62,64,78..79,82..83,119,
                     181,183..184,186,188)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238448"
ORIGIN      
        1 maqikqlfan nvkwsktike dspayfaela qsqhpeylwi gcadsrvpae rltgldsgel
       61 fvhrnvanqv ihtdlnclsv vqyavdvlqv khiiicghyr cggvhaaien lelglinnwl
      121 lhirdiyrkh ksylsslsie eqgnrlcein vaeqvynlgn stilrsawer gqdvkihgwf
      181 ydisdgvlkd lgmnanslkt leavyedama elipdk