MULTISPECIES: DUF294 nucleotidyltransferase-like domain-containing

LOCUS       WP_017004778             627 aa            linear   BCT 26-FEB-2025
            protein [Enterovibrio].
ACCESSION   WP_017004778
VERSION     WP_017004778.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio
  ORGANISM  Enterovibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015410.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03445.19
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterovibrio"
                     /db_xref="taxon:188143"
     Protein         1..627
                     /product="DUF294 nucleotidyltransferase-like
                     domain-containing protein"
                     /GO_function="GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA]"
                     /calculated_mol_wt=71184
     Region          18..>139
                     /region_name="Crp"
                     /note="cAMP-binding domain of CRP or a regulatory subunit
                     of cAMP-dependent protein kinases [Signal transduction
                     mechanisms]; COG0664"
                     /db_xref="CDD:440428"
     Region          155..277
                     /region_name="CBS_pair_CAP-ED_NT_Pol-beta-
                     like_DUF294_assoc"
                     /note="Two tandem repeats of the cystathionine
                     beta-synthase (CBS pair) domains associated with the
                     bacterial CAP_ED (cAMP receptor protein effector domain)
                     family of transcription factors, the NT
                     (Nucleotidyltransferase) Pol-beta-like domain, and the
                     DUF294 dom; cd04587"
                     /db_xref="CDD:341363"
     Site            order(158,160..162,183..185,256,268,270,272..273,276)
                     /site_type="other"
                     /note="putative ligand binding site II [chemical binding]"
                     /db_xref="CDD:341363"
     Region          158..229
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341363"
     Site            order(183,204,208..209,212,234,256..258,272)
                     /site_type="other"
                     /note="putative ligand binding site I [chemical binding]"
                     /db_xref="CDD:341363"
     Region          234..276
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341363"
     Region          305..441
                     /region_name="DUF294"
                     /note="Putative nucleotidyltransferase DUF294; pfam03445"
                     /db_xref="CDD:460919"
     Region          478..621
                     /region_name="DUF294_C"
                     /note="Putative nucleotidyltransferase substrate binding
                     domain; pfam10335"
                     /db_xref="CDD:463050"
ORIGIN      
        1 meaeqieiaa flkqhapfnh lpeevvdeva kqveisyfra dtqlfeygap ihdlcvvrsg
       61 vleiyrrnge lfnrlseggi fgqwgllmnr rvryaakaie dslvyfipdt vfddlferfe
      121 vfsdfmeted ttrlrqaves qsdsndltts kvsslilrdp vtveceatiq qaakimtdeg
      181 vssllvmtte tdeddqettr vvgiitdrdl rsrvialglp yetqvseilt pqlitldhna
      241 yvfeamlaml rnnlhhlpil rhqkpvgvia lsdivryesq sslvivssiy rqqtiddlea
      301 iakgvpacfs rmvsedansh migsamavig rsfkqrllel geeefgpppv pycflalgsm
      361 ardeqlivtd qdnamilddk ydpaehdeyf ahlakfvsdg larcgysyct gnimatnpew
      421 rktrteweac fadwidqpnp ksllnssiff dldgvygatn waetlkafig rrarrnnrfl
      481 acmarnalnr tpplgffknf vmeqdgrhkn smnlkrrgta pladlirvha lavdsrsqns
      541 ferlddiiea gilpkgrged irdamefist vrirhqaldv eadiepdnni epdnlsefer
      601 rnlkdafqil snaqkflkyr yqpnrsn