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UDP-N-acetylglucosamine 4,6-dehydratase (inverting) [Enterovibrio


LOCUS       WP_017004247             331 aa            linear   BCT 04-OCT-2019
            norvegicus].
ACCESSION   WP_017004247
VERSION     WP_017004247.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 331)
  AUTHORS   McNally,D.J., Schoenhofen,I.C., Houliston,R.S., Khieu,N.H.,
            Whitfield,D.M., Logan,S.M., Jarrell,H.C. and Brisson,J.R.
  TITLE     CMP-pseudaminic acid is a natural potent inhibitor of PseB, the
            first enzyme of the pseudaminic acid pathway in Campylobacter
            jejuni and Helicobacter pylori
  JOURNAL   ChemMedChem 3 (1), 55-59 (2008)
   PUBMED   17893902
REFERENCE   2  (residues 1 to 331)
  AUTHORS   McNally,D.J., Hui,J.P., Aubry,A.J., Mui,K.K., Guerry,P.,
            Brisson,J.R., Logan,S.M. and Soo,E.C.
  TITLE     Functional characterization of the flagellar glycosylation locus in
            Campylobacter jejuni 81-176 using a focused metabolomics approach
  JOURNAL   J. Biol. Chem. 281 (27), 18489-18498 (2006)
   PUBMED   16684771
REFERENCE   3  (residues 1 to 331)
  AUTHORS   Schoenhofen,I.C., McNally,D.J., Vinogradov,E., Whitfield,D.,
            Young,N.M., Dick,S., Wakarchuk,W.W., Brisson,J.R. and Logan,S.M.
  TITLE     Functional characterization of dehydratase/aminotransferase pairs
            from Helicobacter and Campylobacter: enzymes distinguishing the
            pseudaminic acid and bacillosamine biosynthetic pathways
  JOURNAL   J. Biol. Chem. 281 (2), 723-732 (2006)
   PUBMED   16286454
REFERENCE   4  (residues 1 to 331)
  AUTHORS   Creuzenet,C.
  TITLE     Characterization of CJ1293, a new UDP-GlcNAc C6 dehydratase from
            Campylobacter jejuni
  JOURNAL   FEBS Lett. 559 (1-3), 136-140 (2004)
   PUBMED   14960321
REFERENCE   5  (residues 1 to 331)
  AUTHORS   Goon,S., Kelly,J.F., Logan,S.M., Ewing,C.P. and Guerry,P.
  TITLE     Pseudaminic acid, the major modification on Campylobacter
            flagellin, is synthesized via the Cj1293 gene
  JOURNAL   Mol. Microbiol. 50 (2), 659-671 (2003)
   PUBMED   14617187
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03589.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     gene            1..331
                     /gene="pseB"
     Protein         1..331
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase
                     (inverting)"
                     /EC_number="4.2.1.115"
                     /calculated_mol_wt=36839
     Region          1..326
                     /region_name="PseB"
                     /note="UDP-N-acetylglucosamine 4,6-dehydratase
                     (inverting); TIGR03589"
                     /db_xref="CDD:132628"
ORIGIN      
        1 mfngksilit ggtgsfgkky tqtilarykp krliilsrde lkqfemqqdf nhpsmryfig
       61 dvrdadrmmq amngvdyvih aaalkqvpaa eynpmecikt nvhgaeniir aaiannvekv
      121 ialstdkaas pnnlygatkl csdklfvaan nmrgesqtqf avvrygnvvg srgsvvpffk
      181 klaaegaesl pvthpnmtrf witlqqgvdf vlknfarmqg geifvpkips vrlidlanay
      241 gnglpikevg irpgekmhei mcpsddshlt lefddhyvmr ptikfysady dyshnplget
      301 gtpvpegfey hsgsnpefld vkqilefeqq s