NADP(H)-dependent aldo-keto reductase [Enterovibrio norvegicus].

LOCUS       WP_016961696             344 aa            linear   BCT 29-NOV-2019
ACCESSION   WP_016961696
VERSION     WP_016961696.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 344)
  AUTHORS   Obmolova,G., Teplyakov,A., Khil,P.P., Howard,A.J.,
            Camerini-Otero,R.D. and Gilliland,G.L.
  TITLE     Crystal structure of the Escherichia coli Tas protein, an
            NADP(H)-dependent aldo-keto reductase
  JOURNAL   Proteins 53 (2), 323-325 (2003)
   PUBMED   14517983
REFERENCE   2  (residues 1 to 344)
  AUTHORS   Johnson,J.M. 3rd, Ding,W., Henkhaus,J. and Fix,D.
  TITLE     Identification of a mutation causing increased expression of the
            tas gene in Escherichia coli FX-11
  JOURNAL   Mutat. Res. 479 (1-2), 121-130 (2001)
   PUBMED   11470487
REFERENCE   3  (residues 1 to 344)
  AUTHORS   Timms,A.R. and Bridges,B.A.
  TITLE     Reversion of the tyrosine ochre strain Escherichia coli WU3610
            under starvation conditions depends on a new gene tas
  JOURNAL   Genetics 148 (4), 1627-1635 (1998)
   PUBMED   9560382
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007912.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10625
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     Protein         1..344
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /GO_function="GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=38440
     Region          1..344
                     /region_name="AKR_SF"
                     /note="Aldo-keto reductase (AKR) superfamily; cl00470"
                     /db_xref="CDD:444925"
     Site            order(19..21,26,48,53,87,130,177..178,203,231..237,240,
                     242,251..253,287,304..308,312,316)
                     /site_type="active"
                     /db_xref="CDD:381320"
     Site            order(48,53,87,130)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381320"
ORIGIN      
        1 mqfhtlphts ldvskiclgt mtfgqqnsea daheqlslal dlgvnfidta emyavpptqe
       61 tqgltekyig swlqksgkrd kvviatkvag prgvpyirdn msldrrnvrq avddslarlq
      121 tdyidlyqvh wpqrhvnsfg qlnythqden sgvslldtld alselvregk iryigvsnet
      181 pwgvmsylrl aekhsltriv siqnpynlln rsfevglsei shqegvella ysplafgvlt
      241 gkylngarpe garctrwerf aryfteqgqa atkayvhlan efsldpaqma lafvnsrsfv
      301 asniigattl dqlktniesi diqlpeelli ridevsakys npcp