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MULTISPECIES: 23S rRNA pseudouridine(2605) synthase RluB


LOCUS       WP_016961321             365 aa            linear   BCT 28-AUG-2024
            [Enterovibrio].
ACCESSION   WP_016961321
VERSION     WP_016961321.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio
  ORGANISM  Enterovibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Czudnochowski,N., Ashley,G.W., Santi,D.V., Alian,A., Finer-Moore,J.
            and Stroud,R.M.
  TITLE     The mechanism of pseudouridine synthases from a covalent complex
            with RNA, and alternate specificity for U2605 versus U2604 between
            close homologs
  JOURNAL   Nucleic Acids Res 42 (3), 2037-2048 (2014)
   PUBMED   24214967
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007976.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10700
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Enterovibrio"
                     /db_xref="taxon:188143"
     gene            1..365
                     /gene="rluB"
     Protein         1..365
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /EC_number="5.4.99.22"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /calculated_mol_wt=40510
     Region          1..290
                     /region_name="PRK10700"
                     /note="23S rRNA pseudouridine(2605) synthase RluB"
                     /db_xref="CDD:182659"
     Region          281..>347
                     /region_name="DUF5877"
                     /note="Family of unknown function (DUF5877); pfam19205"
                     /db_xref="CDD:465994"
ORIGIN      
        1 mseklqkvla raglgsrrei etliqegrvs inglvaklgd rlddvnanir vdghsvqvaa
       61 pselvcrvma ynkpegelct rsdpegrrtv fdrlpklnga rwvavgrlda ntsglmlftt
      121 dgelanrlmh psrqvqreym vrvfgdvneq mvknlvrgvq ledgearfed iqyaggegsn
      181 htfyvviteg rnrevrrlwe tqgvtvsrlk rvrygdiyln kelprggwme leldnvnylr
      241 emvelrpeke tmitveaqkr kargqkirra vrrheerves netrkprrgg psakpvqgnk
      301 paqggkpaqg qgrpasgkpa qgkpgqgkpa qgkrgngrpg gnatpnrggq sssrqkpqgg
      361 krqgr