type I restriction-modification system subunit M [Vibrio

LOCUS       WP_016794251             567 aa            linear   BCT 19-FEB-2025
            cyclitrophicus].
ACCESSION   WP_016794251
VERSION     WP_016794251.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cyclitrophicus
  ORGANISM  Vibrio cyclitrophicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 567)
  AUTHORS   Liu,Y.P., Tang,Q., Zhang,J.Z., Tian,L.F., Gao,P. and Yan,X.X.
  TITLE     Structural basis underlying complex assembly and conformational
            transition of the type I R-M system
  JOURNAL   Proc Natl Acad Sci U S A 114 (42), 11151-11156 (2017)
   PUBMED   28973912
REFERENCE   2  (residues 1 to 567)
  AUTHORS   Sistla,S. and Rao,D.N.
  TITLE     S-Adenosyl-L-methionine-dependent restriction enzymes
  JOURNAL   Crit Rev Biochem Mol Biol 39 (1), 1-19 (2004)
   PUBMED   15121719
REFERENCE   3  (residues 1 to 567)
  AUTHORS   Schubert,H.L., Blumenthal,R.M. and Cheng,X.
  TITLE     Many paths to methyltransfer: a chronicle of convergence
  JOURNAL   Trends Biochem Sci 28 (6), 329-335 (2003)
   PUBMED   12826405
REFERENCE   4  (residues 1 to 567)
  AUTHORS   Williams,R.J.
  TITLE     Restriction endonucleases: classification, properties, and
            applications
  JOURNAL   Mol Biotechnol 23 (3), 225-243 (2003)
   PUBMED   12665693
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13779125
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Vibrio cyclitrophicus"
                     /db_xref="taxon:47951"
     Protein         1..567
                     /product="type I restriction-modification system subunit
                     M"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.72"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /calculated_mol_wt=63750
     Region          12..178
                     /region_name="HsdM_N"
                     /note="HsdM N-terminal domain; pfam12161"
                     /db_xref="CDD:463478"
     Region          190..526
                     /region_name="N6_Mtase"
                     /note="N-6 DNA Methylase; pfam02384"
                     /db_xref="CDD:426749"
ORIGIN      
        1 mnqteqqylk elegklwnaa dklrstldaa qykhavlgli fvkyvsdafk lrqdeikadi
       61 anpeheyyld padfseeela eeiaieleqr dfyteknvfw lptesrwqfl qdngplvigg
      121 aeldingkak kitsvghlid nalegierdn pklkgvlnks ysslkidqak lnelinliat
      181 ipfvhadlns kdilghvyey mlgqfalaeg kkggqfytpa sivtlivemi epfegrvydp
      241 amgsggffvq sekfierhan ekkvdaltqk qkisiygqey nhttwqlaam nmairgldyd
      301 fgkepastyt nvqhpdlrad fimanppfnm kewntgvddn dprfkfgqpp sgnanfawmq
      361 hmlhhlapeg sqalllangs mssttnnegt irqaliendl iecmvalpgq lftntqipac
      421 iwfltknknp rvdkagrklr grkgevlfid arnlgymkdr vlrdfsfddi kkvadlfhaw
      481 ktgeevqgva yedkagfcks atleeitkhd fvltpgryvg ateeeddgvp faekmatlts
      541 klgeqftesa tleaeikknl aglgyel