MULTISPECIES: glucose-1-phosphate thymidylyltransferase RfbA

LOCUS       WP_016784066             295 aa            linear   BCT 09-DEC-2024
            [Vibrio].
ACCESSION   WP_016784066
VERSION     WP_016784066.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 295)
  AUTHORS   Ma,Y., Mills,J.A., Belisle,J.T., Vissa,V., Howell,M., Bowlin,K.,
            Scherman,M.S. and McNeil,M.
  TITLE     Determination of the pathway for rhamnose biosynthesis in
            mycobacteria: cloning, sequencing and expression of the
            Mycobacterium tuberculosis gene encoding
            alpha-D-glucose-1-phosphate thymidylyltransferase
  JOURNAL   Microbiology (Reading) 143 (Pt 3), 937-945 (1997)
   PUBMED   9084178
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01207.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     gene            1..295
                     /gene="rfbA"
     Protein         1..295
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=32515
     Region          2..285
                     /region_name="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; TIGR01207"
                     /db_xref="CDD:130274"
     Site            order(6,8..9,80,83..86,108,144,159..160,170,198)
                     /site_type="active"
                     /note="substrate binding site [active]"
                     /db_xref="CDD:133019"
     Site            order(12,15..17,20..21,25..27,29..32,35,60,112..113,
                     135..138,142..143,221..223,227..228,231,234..236,239..240)
                     /site_type="active"
                     /note="tetramer interface [active]"
                     /db_xref="CDD:133019"
ORIGIN      
        1 mkgivlaggs gtrlypltrg vskqllpiyd kpmvfypist lmlagikdil iittpednag
       61 fqrllgdgsd fginleyaiq pspdglaqaf iigeefigdd svclvlgdni fygqsfsktl
      121 qsaasresga tvfgyqvkdp erfgvvefdd emkaisieek peapksnyav tglyfydnrv
      181 vemakqvkps hrgeleittl nemylndgsl nvellgrgfa wldtgthesl heassfvqti
      241 envqglkvac leeiawrngw lsdeqvltla kpmmkneygq yltrlvnetq skavk