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MULTISPECIES: outer membrane channel protein TolC [Salmonella].


LOCUS       WP_014343899             491 aa            linear   BCT 10-SEP-2020
ACCESSION   WP_014343899
VERSION     WP_014343899.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 491)
  AUTHORS   Raczkowska,A., Trzos,J., Lewandowska,O., Nieckarz,M. and
            Brzostek,K.
  TITLE     Expression of the AcrAB Components of the AcrAB-TolC Multidrug
            Efflux Pump of Yersinia enterocolitica Is Subject to Dual
            Regulation by OmpR
  JOURNAL   PLoS ONE 10 (4), e0124248 (2015)
   PUBMED   25893523
REFERENCE   2  (residues 1 to 491)
  AUTHORS   Koronakis,V., Sharff,A., Koronakis,E., Luisi,B. and Hughes,C.
  TITLE     Crystal structure of the bacterial membrane protein TolC central to
            multidrug efflux and protein export
  JOURNAL   Nature 405 (6789), 914-919 (2000)
   PUBMED   10879525
REFERENCE   3  (residues 1 to 491)
  AUTHORS   Koronakis,V., Li,J., Koronakis,E. and Stauffer,K.
  TITLE     Structure of TolC, the outer membrane component of the bacterial
            type I efflux system, derived from two-dimensional crystals
  JOURNAL   Mol. Microbiol. 23 (3), 617-626 (1997)
   PUBMED   9044294
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007002.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09465
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..491
                     /gene="tolC"
     Protein         1..491
                     /product="outer membrane channel protein TolC"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=53555
     Region          3..450
                     /region_name="tolC"
                     /note="outer membrane channel protein; Reviewed; PRK09465"
                     /db_xref="CDD:236529"
ORIGIN      
        1 mqmkkllpil iglslsgfst lsqaenlmqv yqqarlsnpe lrksaadrda afekinears
       61 pllpqlglga dytysngyrd anginsnets aslqltqtlf dmskwrgltl qekaagiqdv
      121 tyqtdqqtli lntanayfkv lnaidvlsyt qaqkeaiyrq ldqttqrfnv glvaitdvqn
      181 araqydtvla nevtarnnld naveelrqvt gnyypelasl nvehfktdkp kavnallkea
      241 enrnlsllqa rlsqdlareq irqaqdghlp tlnltastgi sdtsysgskt nstqyddsnm
      301 gqnkiglnfs lplyqggmvn sqvkqaqynf vgaseqlesa hrsvvqtvrs sfnninasis
      361 sinaykqavv saqssldame agysvgtrti vdvldatttl ydakqqlana rytylinqln
      421 ikyalgtlne qdllalnstl gkpiptspes vapetpdqda aadgynahsa apavqptaar
      481 ansnngnpfr h