MULTISPECIES: LysR family transcriptional regulator [Klebsiella].

LOCUS       WP_014343450             323 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_014343450
VERSION     WP_014343450.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 323)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 323)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444111
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..323
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=35295
     Region          23..81
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          111..312
                     /region_name="PBP2_CrgA_like_2"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08471"
                     /db_xref="CDD:176160"
     Site            order(121,125,164,178,180,243,260,287)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176160"
     Site            order(122..123,127..128,130..131,134,138,140..146,207,
                     237..241,248..249,252)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176160"
ORIGIN      
        1 mkndntgkva iifpqngrim drlsamallv kvtelgsmsa aaralnmplt tvsrhigele
       61 salgvrllar ttrkltltda gvdyvaaarr ileevenaer qatgeyqepk gelvisaptm
      121 fgrqhvlpvi sefiarypli rvrlllsdrn adlvsdhvdl avrigdlads smvatrlgtm
      181 rivacahpal lakygepqrp rdlaalpiir iespmpyrgw rfraaeredq linlppvlsv
      241 ttpesaadaa rlgvgvarll hyqaldglrh gelrlllenv epdpapvhll ytardlaplk
      301 lrkfidfaap alrqallria gaa