sugar porter family MFS transporter [Klebsiella pneumoniae].

LOCUS       WP_014343424             478 aa            linear   BCT 24-MAR-2023
ACCESSION   WP_014343424
VERSION     WP_014343424.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 478)
  AUTHORS   Custodio,T.F., Paulsen,P.A., Frain,K.M. and Pedersen,B.P.
  TITLE     Structural comparison of GLUT1 to GLUT3 reveal transport regulation
            mechanism in sugar porter family
  JOURNAL   Life Sci Alliance 4 (4), e202000858 (2021)
   PUBMED   33536238
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 478)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   3  (residues 1 to 478)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11489872
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..478
                     /product="sugar porter family MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=52315
     Region          17..462
                     /region_name="SP"
                     /note="MFS transporter, sugar porter (SP) family;
                     TIGR00879"
                     /db_xref="CDD:273317"
     Site            order(41,45,159,162..163,166,274..275,279..280,283..284,
                     312,377..378,381..382,386,409..410,413)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340873"
ORIGIN      
        1 mwqekmtsis ndstlsprtq rdtrrmnwfv siaaavagll fgldigvisg alpfitdhft
       61 lssqlqewvv ssmmlgaaig alfngwlsfr lgrkyslmag avlfvagsig safaasvevl
      121 lvarvvlgva vgiasytapl ylsemasenv rgkmismyql mvtlgivlaf lsdtafsysg
      181 nwramlgvla lpaviliilv vflpnsprwl aekgrhieae evlrmlrdts ekardelnei
      241 reslklkqgg walfkvnrnv rravflgmll qamqqftgmn iimyyaprif kmagfttteq
      301 qmiatlvvgl tfmfatfiav ftvdkagrkp alkigfsvma lgtlvlgycl mqfdngtass
      361 glswlsvgmt mmciagyams aapvvwilcs eiqplkcrdf gitcstttnw vsnmiigatf
      421 ltlldaigaa gtfwlytaln vafigitfwl ipetknvtle hiernlmage klrnignr