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LOCUS WP_014343341 637 aa linear BCT 11-DEC-2019 ACCESSION WP_014343341 VERSION WP_014343341.1 KEYWORDS RefSeq. SOURCE Klebsiella pneumoniae ORGANISM Klebsiella pneumoniae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella; Klebsiella pneumoniae complex. REFERENCE 1 (residues 1 to 637) AUTHORS Ochsner,U.A., Young,C.L., Stone,K.C., Dean,F.B., Janjic,N. and Critchley,I.A. TITLE Mode of action and biochemical characterization of REP8839, a novel inhibitor of methionyl-tRNA synthetase JOURNAL Antimicrob. Agents Chemother. 49 (10), 4253-4262 (2005) PUBMED 16189106 REFERENCE 2 (residues 1 to 637) AUTHORS Nakanishi,K., Ogiso,Y., Nakama,T., Fukai,S. and Nureki,O. TITLE Structural basis for anticodon recognition by methionyl-tRNA synthetase JOURNAL Nat. Struct. Mol. Biol. 12 (10), 931-932 (2005) PUBMED 16155581 REFERENCE 3 (residues 1 to 637) AUTHORS Datta,D., Vaidehi,N., Zhang,D. and Goddard,W.A. 3rd. TITLE Selectivity and specificity of substrate binding in methionyl-tRNA synthetase JOURNAL Protein Sci. 13 (10), 2693-2705 (2004) PUBMED 15388861 REFERENCE 4 (residues 1 to 637) AUTHORS Serre,L., Verdon,G., Choinowski,T., Hervouet,N., Risler,J.L. and Zelwer,C. TITLE How methionyl-tRNA synthetase creates its amino acid recognition pocket upon L-methionine binding JOURNAL J. Mol. Biol. 306 (4), 863-876 (2001) PUBMED 11243794 REFERENCE 5 (residues 1 to 637) AUTHORS Mechulam,Y., Schmitt,E., Maveyraud,L., Zelwer,C., Nureki,O., Yokoyama,S., Konno,M. and Blanquet,S. TITLE Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features JOURNAL J. Mol. Biol. 294 (5), 1287-1297 (1999) PUBMED 10600385 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF001100.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK00133 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..637 /organism="Klebsiella pneumoniae" /db_xref="taxon:573" gene 1..637 /gene="metG" Protein 1..637 /product="methionine--tRNA ligase" /EC_number="6.1.1.10" /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0004825 - methionine-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_process="GO:0006431 - methionyl-tRNA aminoacylation [Evidence IEA]" /calculated_mol_wt=71446 Region 1..637 /region_name="metG" /note="methionyl-tRNA synthetase; Reviewed; PRK00133" /db_xref="CDD:234655" ORIGIN 1 mrghevnfic addahgtpim lkaqqlgitp eqmigemsqe hqtdfagfdi sydnyhsths 61 denrelseli ytrlkengfi knrtisqlyd pekgmflpdr fvkgtcpkck spdqygdnce 121 vcgatyspte lidpksvvsg atpvmrdseh fffdlpsfse mlqawtrsga lqeqvankmq 181 ewfesglqqw disrdapyfg feipnapgky fyvwldapig ymgsfknlcd krgdttsfde 241 ywkkdstael yhfigkdivy fhslfwpaml egsnfrkptn lfvhgyvtvn gakmsksrgt 301 fikastwlnh fdadslryyy taklssridd idlnledfvq rvnadivnkv vnlasrnagf 361 iskrfngvla aeladpalyk tftdaaesig eawdsrefgk aireimalad vanryvdeqa 421 pwvvakqegr dadlqaictm glnmfrvlmt wlkpvlpqla araeaflnse lswdaiqqpl 481 lahkvnpfka lynriemkqv ealveaskee vkataapvtg pladdpiqet itfddfakvd 541 lrvalienae fvegsdkllr ltldlggekr nvfsgirsay pdpqpligrl tvmvanlapr 601 kmrfgisegm vmaagpggkd ifllspddga kpgqqvk