MULTISPECIES: NCS2 family permease [Klebsiella].

LOCUS       WP_014343337             447 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_014343337
VERSION     WP_014343337.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 447)
  AUTHORS   Koukaki,M., Vlanti,A., Goudela,S., Pantazopoulou,A., Gioule,H.,
            Tournaviti,S. and Diallinas,G.
  TITLE     The nucleobase-ascorbate transporter (NAT) signature motif in UapA
            defines the function of the purine translocation pathway
  JOURNAL   J Mol Biol 350 (3), 499-513 (2005)
   PUBMED   15953615
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10789293
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..447
                     /product="NCS2 family permease"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /calculated_mol_wt=46503
     Region          13..446
                     /region_name="NCS2"
                     /note="Xanthine/guanine/uracil/vitamin C permease
                     GhxP/GhxQ, nucleobase:cation symporter 2 (NCS2) family
                     [Nucleotide transport and metabolism]; COG2252"
                     /db_xref="CDD:441853"
ORIGIN      
        1 madntlhssa rdnwlerrfa lrsrggtlrt eclagitgfl aaayllvvip gllaiggmdk
       61 gaattgtilv fvvgsllmaf yanlpfivgp giggsvlvgv tlagsegigw qtglgiacws
      121 gvlfflltrf glrevvtrsv pqsiklglta siglfvavlg frnaglvlan aktnalmlgd
      181 flapsalval cglflaialq arkvpgailw ailcatlvgi pfgvtklpth fidvphslap
      241 vlgqvdllga lniaflpflf vffaseffst mgttlavgge aglldeegnm pqinrpfmvd
      301 siaaalgpwv gipaatalie ssaaaeaggk tgltalsaav mfllmllftp valmipkeat
      361 apaliligln mfsglrkvdl anftdglpvl mmvmitlian sfgtgiaggl lfyivikaia
      421 gkwreipigl wvlavplvyy fatlvrh