Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

dicarboxylate/amino acid:cation symporter [Klebsiella pneumoniae].


LOCUS       WP_014343325             410 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_014343325
VERSION     WP_014343325.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 410)
  AUTHORS   Grewer,C., Gameiro,A. and Rauen,T.
  TITLE     SLC1 glutamate transporters
  JOURNAL   Pflugers Arch 466 (1), 3-24 (2014)
   PUBMED   24240778
REFERENCE   2  (residues 1 to 410)
  AUTHORS   Kanai,Y., Clemencon,B., Simonin,A., Leuenberger,M., Lochner,M.,
            Weisstanner,M. and Hediger,M.A.
  TITLE     The SLC1 high-affinity glutamate and neutral amino acid transporter
            family
  JOURNAL   Mol Aspects Med 34 (2-3), 108-120 (2013)
   PUBMED   23506861
REFERENCE   3  (residues 1 to 410)
  AUTHORS   Gesemann,M., Lesslauer,A., Maurer,C.M., Schonthaler,H.B. and
            Neuhauss,S.C.
  TITLE     Phylogenetic analysis of the vertebrate excitatory/neutral amino
            acid transporter (SLC1/EAAT) family reveals lineage specific
            subfamilies
  JOURNAL   BMC Evol Biol 10, 117 (2010)
   PUBMED   20429920
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 410)
  AUTHORS   Kanai,Y. and Hediger,M.A.
  TITLE     The glutamate/neutral amino acid transporter family SLC1:
            molecular, physiological and pharmacological aspects
  JOURNAL   Pflugers Arch 447 (5), 469-479 (2004)
   PUBMED   14530974
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10003465
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..410
                     /product="dicarboxylate/amino acid:cation symporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /calculated_mol_wt=43290
     Region          1..400
                     /region_name="GltP"
                     /note="Na+/H+-dicarboxylate symporter [Energy production
                     and conversion]; COG1301"
                     /db_xref="CDD:440912"
ORIGIN      
        1 mlmgilsgaa ihayatpttv sawadnitll tdlflrlikm viaplvfstl tvgimrlget
       61 atigrvggka mvwfitssvl silvglvivt fqhpgaglnl avpreavdtg lavsgmslkg
      121 flshtiptsi teamanneil qivvfsmffg iagaslgekf naplvaalnv vshimlkvtg
      181 yvmyvaplai faaissvias qglgillnya sfiggyylav lltsavliav gymvlkkevf
      241 rllnmlkdpv lvafttssse aaypktlerl vkfgcsrniv sfvlpigysf nlvgsmvycs
      301 faamfiaqay nvplsfseit vmmltlmlas kgiagvprsa lvvlaatips fnipvagill
      361 lmgidhfldm grsainvlgn giatamlskn eglltdeeaq pdwevekaea