lipoyl protein ligase domain-containing protein [Klebsiella

LOCUS       WP_014343290             246 aa            linear   BCT 02-MAR-2025
            pneumoniae].
ACCESSION   WP_014343290
VERSION     WP_014343290.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 246)
  AUTHORS   Fujiwara,K., Hosaka,H., Matsuda,M., Okamura-Ikeda,K., Motokawa,Y.,
            Suzuki,M., Nakagawa,A. and Taniguchi,H.
  TITLE     Crystal structure of bovine lipoyltransferase in complex with
            lipoyl-AMP
  JOURNAL   J Mol Biol 371 (1), 222-234 (2007)
   PUBMED   17570395
REFERENCE   2  (residues 1 to 246)
  AUTHORS   Ma,Q., Zhao,X., Nasser Eddine,A., Geerlof,A., Li,X., Cronan,J.E.,
            Kaufmann,S.H. and Wilmanns,M.
  TITLE     The Mycobacterium tuberculosis LipB enzyme functions as a
            cysteine/lysine dyad acyltransferase
  JOURNAL   Proc Natl Acad Sci U S A 103 (23), 8662-8667 (2006)
   PUBMED   16735476
REFERENCE   3  (residues 1 to 246)
  AUTHORS   McManus,E., Luisi,B.F. and Perham,R.N.
  TITLE     Structure of a putative lipoate protein ligase from Thermoplasma
            acidophilum and the mechanism of target selection for
            post-translational modification
  JOURNAL   J Mol Biol 356 (3), 625-637 (2006)
   PUBMED   16384580
REFERENCE   4  (residues 1 to 246)
  AUTHORS   Kim,D.J., Kim,K.H., Lee,H.H., Lee,S.J., Ha,J.Y., Yoon,H.J. and
            Suh,S.W.
  TITLE     Crystal structure of lipoate-protein ligase A bound with the
            activated intermediate: insights into interaction with lipoyl
            domains
  JOURNAL   J Biol Chem 280 (45), 38081-38089 (2005)
   PUBMED   16141198
REFERENCE   5  (residues 1 to 246)
  AUTHORS   Fujiwara,K., Toma,S., Okamura-Ikeda,K., Motokawa,Y., Nakagawa,A.
            and Taniguchi,H.
  TITLE     Crystal structure of lipoate-protein ligase A from Escherichia
            coli. Determination of the lipoic acid-binding site
  JOURNAL   J Biol Chem 280 (39), 33645-33651 (2005)
   PUBMED   16043486
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF046470.2
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF21948.1
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..246
                     /product="lipoyl protein ligase domain-containing protein"
                     /calculated_mol_wt=26184
     Region          34..245
                     /region_name="BPL_LplA_LipB"
                     /note="biotin-lipoate ligase family; cl14057"
                     /db_xref="CDD:449326"
     Site            order(48,54..57,88..92,98..100,149..150,161,164..166,
                     183..185,187)
                     /site_type="active"
                     /db_xref="CDD:319740"
ORIGIN      
        1 msqltladcw prrfspssla lqfcedptqa eqplfakasa geavaqlwqa pqglvvpgsy
       61 rqftdlpais ahfaargwpv wlrrsggglv pqgpgiinls lawpvqqplg eaaepiyhsl
      121 cavlqrtlar fgvashprav sgsfcdgryn lacgegaear kivgtaqywr plaaggghvv
      181 lahavilida dlsaahqaan afeaqlgser vycadktvtl aqllpgerhl lprfsetlaq
      241 eldaar