MDR family oxidoreductase [Klebsiella pneumoniae].

LOCUS       WP_014343284             267 aa            linear   BCT 06-NOV-2024
ACCESSION   WP_014343284
VERSION     WP_014343284.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 267)
  AUTHORS   Persson,B., Hedlund,J. and Jornvall,H.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the MDR superfamily
  JOURNAL   Cell Mol Life Sci 65 (24), 3879-3894 (2008)
   PUBMED   19011751
REFERENCE   2  (residues 1 to 267)
  AUTHORS   Auld,D.S. and Bergman,T.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : The role of zinc for alcohol dehydrogenase structure and
            function
  JOURNAL   Cell Mol Life Sci 65 (24), 3961-3970 (2008)
   PUBMED   19011745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10169682
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..267
                     /product="MDR family oxidoreductase"
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /calculated_mol_wt=27978
     Region          1..265
                     /region_name="MDR_yhdh"
                     /note="Yhdh putative quinone oxidoreductases; cd08288"
                     /db_xref="CDD:176248"
     Site            order(68..69,72,96,98..101,120..122,140,160..161,182..186,
                     207..210,252,255,257)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:176248"
     Site            order(148,175,181..184,190,192..195,197..199,201..208,
                     211..212)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:176248"
ORIGIN      
        1 mvpgidfagq vkesrdprfv pgqaviltgw gvgenhwggl ateacvkgdw lvalpetlsa
       61 rqamiigtag ftamlcvdal vsagvtpdsg dilvtgasgg vgstavvllk algyrvtavs
      121 gresthdylr qlgadtilpr sdfaetrple kqlwagavdt vggpvlakvl aqtqyrgcva
      181 acglaggfdl pttvmpfilr nvrlqgvdsv mvptaerdav wlrlaqllpe syyqqaatei
      241 tleqapayaa dflsnnihgr tlvnigq