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LOCUS WP_014343269 2035 aa linear BCT 11-OCT-2023 pneumoniae]. ACCESSION WP_014343269 VERSION WP_014343269.1 KEYWORDS RefSeq. SOURCE Klebsiella pneumoniae ORGANISM Klebsiella pneumoniae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella; Klebsiella pneumoniae complex. REFERENCE 1 (residues 1 to 2035) AUTHORS Miller,D.A., Luo,L., Hillson,N., Keating,T.A. and Walsh,C.T. TITLE Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis JOURNAL Chem Biol 9 (3), 333-344 (2002) PUBMED 11927258 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: BlastRule Evidence Accession :: NBR005924 Evidence Source :: NCBI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..2035 /organism="Klebsiella pneumoniae" /db_xref="taxon:573" gene 1..2035 /gene="irp2" Protein 1..2035 /product="yersiniabactin non-ribosomal peptide synthetase HMWP2" /GO_function="GO:1904091 - non-ribosomal peptide synthetase activity [Evidence IEA]" /calculated_mol_wt=228463 Region <5..95 /region_name="AcpA" /note="Acyl carrier protein/domain [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; COG3433" /db_xref="CDD:442659" Region 95..1445 /region_name="EntF" /note="seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism]; COG1020" /db_xref="CDD:440643" Region 580..1063 /region_name="A_NRPS_TlmIV_like" /note="The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; cd12114" /db_xref="CDD:341279" Site order(709,712..717,719..720) /site_type="other" /note="acyl-activating enzyme (AAE) consensus motif" /db_xref="CDD:341279" Site order(712..713,831..832,853..858,881,943,955,958,1058) /site_type="other" /note="AMP binding site [chemical binding]" /db_xref="CDD:341279" Region 1495..1906 /region_name="Cyc_NRPS" /note="Cyc (heterocyclization) domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family; cd19535" /db_xref="CDD:380458" Region 1950..2008 /region_name="PP-binding" /note="Phosphopantetheine attachment site; pfam00550" /db_xref="CDD:425746" ORIGIN 1 misgapsqds llpdnrhaad yqqlrerliq elnltpqqlh eesnliqagl dsirlmrwlh 61 wfrkngyrlt lrelyaaptl aawnqlmlsr spenaeeetp pdesswpnmt estpfpltpv 121 qhayltgrmp gqtlggvgch lyqefeghcl tasqleqait tllqrhpmlh iafrpdgqqv 181 wlpqpywngv tvhdlshnda esrqayldal rqrlshrllr veigetfdfq ltllpdnrhr 241 lhvnidllim dassftlffd elnallages lpaidtrydf rsyllhqqki nqtlrddara 301 ywlakastlp papvlplace patlrevrnt rrrmivpatr whafsnrage ygvtptmala 361 tcfsavlarw ggltrlllni tlfdrqplhp avgamladft nillldtacd gdtvsnlark 421 nqltftedwe hrhwsgvell relkrqqryp hgapvvftsn lgrslyssra esplgepewg 481 isqtpqvwid hlafehhgev wlqwdsndal fppalvetlf daycqlinql cddesawqkp 541 fadmmpasqr airervnatg apipegllhe gifrialqqp qalavtdmry qwnyheltdy 601 arrcagrlie cgvqpgdnva itmskgagql vavlavllag avyvpvsldq paarrekiya 661 dasvrlvlic qhdtsagsdd ipvlawqqai eaepianpvv raptqpayii ytsgstgtpk 721 gvvishrgal ntccdintry qvgphdrvla lsalhfdlsv ydifgvlrag galvmvmenq 781 rrdphawcel iqrhqvtlwn svpalfdmll twcegfadat penlravmls gdwigldlpa 841 ryrafrpqgq fiamggatea siwsnaceih dvpahwrsip ygfpltnqry rvvdeqgrdc 901 pdwvpgelwi ggigvaegyf ndplrseqqf ltlpderwyr tgdlgcywpd gtieflgrrd 961 kqvkvggyri elgeiesals qlagvkqatv laigekektl aayvvpqgea fcvtdhrnpa 1021 lpqawhtlag tlpccaispe isaeqvadfl qhrllklkpg htagadplpl mnslaiqprw 1081 qavvelwlaf lvtqrrlkpa aegyqvcage ehedehphfs ghdltlsqil rgarnelsll 1141 ndaqwspesl afnhpasapy iqelaticqq laqrlqrpvr lldvgtrtgr aaesllaqln 1201 agqieyvgle qsqemllsar qrlapwpgar lslwnadtla ahahsadiiw lnnalhrllp 1261 edpgllatlq hlavpgally vmefrqltps allstllltn gqpeallhns adwaalfsaa 1321 afncqhgdev aglqrflvqc pdrqvrrdpr qlqaalagrl pgwmvpqriv fldalpltan 1381 gkidyqalkr rhtpeaenpa eadlpqgdie kqvaalwqql lstgnvtret dffqqggdsl 1441 latrltgqlh qagyeaqlsd lfnhprladf aatlrktdvp veqpfvhspe eryqpfaltd 1501 vqqaylvgrq pgfalggvgs hffvefeiad ldltrletvw nrliarhdml raivrdgqqq 1561 vleqtppwvi pthtlhtpee alrvreklah qvlnpevwpv fdlqvgyvdg mparlwlcld 1621 nllldglsmq illaelehgy rypqqllppl pvtfrdylqq pslqspnpds lawwqaqldd 1681 ippapalplr clpqevetpr farlngalds trwhrlkkra adahltpsav llsvwstvls 1741 awsaqpeftl nltlfdrrpl hpqinqilgd ftslmllswh pgeswlhsaq slqqrlsqnl 1801 nhrdvsairv mrqlaqrqnv pavpmpvvft salgfeqdnf larrnllkpv wgisqtpqvw 1861 ldhqiyeseg elrfnwdfva alfpagqver qfeqycalln rmaedesgwq lplaalvppv 1921 khagqcaers prvcpehsqp hiaadestvs licdafrevv gesvtpaenf feagatslnl 1981 vqlhvllqrh efstltlldl fthpspaala dylagvatve ktkrprpvrr rqrri