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MULTISPECIES: sodium/proton antiporter NhaB [Klebsiella].


LOCUS       WP_014343233             516 aa            linear   BCT 17-OCT-2022
ACCESSION   WP_014343233
VERSION     WP_014343233.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 516)
  AUTHORS   Radchenko,M.V., Waditee,R., Oshimi,S., Fukuhara,M., Takabe,T. and
            Nakamura,T.
  TITLE     Cloning, functional expression and primary characterization of
            Vibrio parahaemolyticus K+/H+ antiporter genes in Escherichia coli
  JOURNAL   Mol Microbiol 59 (2), 651-663 (2006)
   PUBMED   16390457
REFERENCE   2  (residues 1 to 516)
  AUTHORS   Herz,K., Vimont,S., Padan,E. and Berche,P.
  TITLE     Roles of NhaA, NhaB, and NhaD Na+/H+ antiporters in survival of
            Vibrio cholerae in a saline environment
  JOURNAL   J Bacteriol 185 (4), 1236-1244 (2003)
   PUBMED   12562793
REFERENCE   3  (residues 1 to 516)
  AUTHORS   Nakamura,T., Fujisaki,Y., Enomoto,H., Nakayama,Y., Takabe,T.,
            Yamaguchi,N. and Uozumi,N.
  TITLE     Residue aspartate-147 from the third transmembrane region of
            Na(+)/H(+) antiporter NhaB of Vibrio alginolyticus plays a role in
            its activity
  JOURNAL   J Bacteriol 183 (19), 5762-5767 (2001)
   PUBMED   11544242
REFERENCE   4  (residues 1 to 516)
  AUTHORS   Pinner,E., Padan,E. and Schuldiner,S.
  TITLE     Kinetic properties of NhaB, a Na+/H+ antiporter from Escherichia
            coli
  JOURNAL   J Biol Chem 269 (42), 26274-26279 (1994)
   PUBMED   7929345
REFERENCE   5  (residues 1 to 516)
  AUTHORS   Pinner,E., Kotler,Y., Padan,E. and Schuldiner,S.
  TITLE     Physiological role of nhaB, a specific Na+/H+ antiporter in
            Escherichia coli
  JOURNAL   J Biol Chem 268 (3), 1729-1734 (1993)
   PUBMED   8093613
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007093.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09547
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..516
                     /gene="nhaB"
     Protein         1..516
                     /product="sodium/proton antiporter NhaB"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /calculated_mol_wt=56622
     Region          1..510
                     /region_name="nhaB"
                     /note="sodium/proton antiporter NhaB; PRK09547"
                     /db_xref="CDD:181942"
     Site            order(69..76,91..108,131..145,147..151,161..173,200..223,
                     245..259,297..309,317..331,346..364,388..403,430..443,
                     448..453,479..491)
                     /site_type="other"
                     /note="transmembrane helices"
                     /db_xref="CDD:238344"
ORIGIN      
        1 meisygralw rnflgqspdw yklaliifli vnplvfavap fvagwllvve fiftlamalk
       61 cypllpggll aiealligmt spahvreeia gnlevllllm fmvagiyfmk qlllfvftrl
      121 llgirskmll slafclaaaf lsafldaltv vavvisvavg fygiyhrvas arpddsdlld
      181 dshieqhyre vleqfrgflr slmmhagvgt alggvmtmvg epqnliiaka agwhfgeffl
      241 rmapvtlpvm vcglltcllv ekyrlfgyge plpptvrkvl qefddrsraq rsrqerlrli
      301 aqaligvwli valafhlaev gliglsviil attftgvtde haigkaftea lpftalltvf
      361 fsivaviidq qlftpviefv lqasphaqls lfylfnglls sisdnvfvgt vyineakaal
      421 ehgaislpqf emlavaintg tnlpsvatpn gqaaflfllt salaplirls ygrmvwmalp
      481 ytivltlvgl lcveftlmpv tdwllahgwl vtptlp