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pyruvate formate lyase family protein, partial [Klebsiella


LOCUS       WP_014343221             337 aa            linear   BCT 02-MAR-2025
            pneumoniae].
ACCESSION   WP_014343221
VERSION     WP_014343221.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 337)
  AUTHORS   Craciun,S. and Balskus,E.P.
  TITLE     Microbial conversion of choline to trimethylamine requires a glycyl
            radical enzyme
  JOURNAL   Proc Natl Acad Sci U S A 109 (52), 21307-21312 (2012)
   PUBMED   23151509
REFERENCE   2  (residues 1 to 337)
  AUTHORS   O'Brien,J.R., Raynaud,C., Croux,C., Girbal,L., Soucaille,P. and
            Lanzilotta,W.N.
  TITLE     Insight into the mechanism of the B12-independent glycerol
            dehydratase from Clostridium butyricum: preliminary biochemical and
            structural characterization
  JOURNAL   Biochemistry 43 (16), 4635-4645 (2004)
   PUBMED   15096031
REFERENCE   3  (residues 1 to 337)
  AUTHORS   Selmer,T. and Andrei,P.I.
  TITLE     p-Hydroxyphenylacetate decarboxylase from Clostridium difficile. A
            novel glycyl radical enzyme catalysing the formation of p-cresol
  JOURNAL   Eur J Biochem 268 (5), 1363-1372 (2001)
   PUBMED   11231288
REFERENCE   4  (residues 1 to 337)
  AUTHORS   Becker,A., Fritz-Wolf,K., Kabsch,W., Knappe,J., Schultz,S. and
            Volker Wagner,A.F.
  TITLE     Structure and mechanism of the glycyl radical enzyme pyruvate
            formate-lyase
  JOURNAL   Nat Struct Biol 6 (10), 969-975 (1999)
   PUBMED   10504733
REFERENCE   5  (residues 1 to 337)
  AUTHORS   Leuthner,B., Leutwein,C., Schulz,H., Horth,P., Haehnel,W.,
            Schiltz,E., Schagger,H. and Heider,J.
  TITLE     Biochemical and genetic characterization of benzylsuccinate
            synthase from Thauera aromatica: a new glycyl radical enzyme
            catalysing the first step in anaerobic toluene metabolism
  JOURNAL   Mol Microbiol 28 (3), 615-628 (1998)
   PUBMED   9632263
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF014900.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF02901.20
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         <1..>337
                     /product="pyruvate formate lyase family protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
     Region          <1..333
                     /region_name="RNR_PFL"
                     /note="Ribonucleotide reductase and Pyruvate formate
                     lyase; cl38938"
                     /db_xref="CDD:476821"
ORIGIN      
        1 mvigkqmqff garanlaktl lyainggvde klkiqvgpkt dplrdevldy dtvmasldhf
       61 mdwlavqyis alniihcmhd kysyeaalma lhdrdvyrtm acgiaglsva adslsaikya
      121 rvkpvrdhhg lavdfviegd ypqygnnddr vdaiacdlve rfmrkiqalp twrqavptqs
      181 iltitsnvvy gqktgntpdg rragtpfapg anpmhgrdrk gavasltsva klpftyakdg
      241 isytfsivpa algkapsaqe nnlvglldgy fhheetvegg qhlnvnvlnr eklldaiehp
      301 eqypnltirv sgyavrfnal treqqqdvis rtftsql