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MULTISPECIES: formylglycine-generating enzyme family protein


LOCUS       WP_014343203             297 aa            linear   BCT 24-DEC-2024
            [Enterobacteriaceae].
ACCESSION   WP_014343203
VERSION     WP_014343203.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Appel,M.J., Meier,K.K., Lafrance-Vanasse,J., Lim,H., Tsai,C.L.,
            Hedman,B., Hodgson,K.O., Tainer,J.A., Solomon,E.I. and
            Bertozzi,C.R.
  TITLE     Formylglycine-generating enzyme binds substrate directly at a
            mononuclear Cu(I) center to initiate O2 activation
  JOURNAL   Proc Natl Acad Sci U S A 116 (12), 5370-5375 (2019)
   PUBMED   30824597
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Knop,M., Dang,T.Q., Jeschke,G. and Seebeck,F.P.
  TITLE     Copper is a Cofactor of the Formylglycine-Generating Enzyme
  JOURNAL   Chembiochem 18 (2), 161-165 (2017)
   PUBMED   27862795
REFERENCE   3  (residues 1 to 297)
  AUTHORS   Bojarova,P. and Williams,S.J.
  TITLE     Sulfotransferases, sulfatases and formylglycine-generating enzymes:
            a sulfation fascination
  JOURNAL   Curr Opin Chem Biol 12 (5), 573-581 (2008)
   PUBMED   18625336
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11441389
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..297
                     /product="formylglycine-generating enzyme family protein"
                     /calculated_mol_wt=32946
     Region          40..296
                     /region_name="YfmG"
                     /note="Formylglycine-generating enzyme, required for
                     sulfatase activity, contains SUMF1/FGE domain
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG1262"
                     /db_xref="CDD:440874"
ORIGIN      
        1 menniiaisv tvcllvgcdq gnaarsekaa kelvgkslsn mipvqggefl mgdfgplvge
       61 klpfsinqdd kvlhkvvlsd fsiskykvtn ddynkylrit gvkkppinil lkdypslqkg
      121 dysvgitwqq akdycqwlgk esgkkfdlpt eaqweyaars rgqyipfatn ngeflpgkni
      181 psqdelseyt dgagipiypv gkyppnplgl ydmglsgsew tndwyasdyy shspvndpqg
      241 pvkgtekvlr gnvggdrqya ltvfrqsdlp vpkinkdddy ekygvgpqyv frcvink