Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: formylglycine-generating enzyme family protein


LOCUS       WP_014343198             190 aa            linear   BCT 23-DEC-2024
            [Klebsiella].
ACCESSION   WP_014343198
VERSION     WP_014343198.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 190)
  AUTHORS   Appel,M.J., Meier,K.K., Lafrance-Vanasse,J., Lim,H., Tsai,C.L.,
            Hedman,B., Hodgson,K.O., Tainer,J.A., Solomon,E.I. and
            Bertozzi,C.R.
  TITLE     Formylglycine-generating enzyme binds substrate directly at a
            mononuclear Cu(I) center to initiate O2 activation
  JOURNAL   Proc Natl Acad Sci U S A 116 (12), 5370-5375 (2019)
   PUBMED   30824597
REFERENCE   2  (residues 1 to 190)
  AUTHORS   Knop,M., Dang,T.Q., Jeschke,G. and Seebeck,F.P.
  TITLE     Copper is a Cofactor of the Formylglycine-Generating Enzyme
  JOURNAL   Chembiochem 18 (2), 161-165 (2017)
   PUBMED   27862795
REFERENCE   3  (residues 1 to 190)
  AUTHORS   Bojarova,P. and Williams,S.J.
  TITLE     Sulfotransferases, sulfatases and formylglycine-generating enzymes:
            a sulfation fascination
  JOURNAL   Curr Opin Chem Biol 12 (5), 573-581 (2008)
   PUBMED   18625336
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11441389
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..190
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..190
                     /product="formylglycine-generating enzyme family protein"
                     /calculated_mol_wt=21210
     Region          <13..189
                     /region_name="YfmG"
                     /note="Formylglycine-generating enzyme, required for
                     sulfatase activity, contains SUMF1/FGE domain
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG1262"
                     /db_xref="CDD:440874"
ORIGIN      
        1 mdilakrhps llkgdypagv iwqqakdycq wlgkksgkki dlpteaqwef aarsrgqylp
       61 fatnngefsp gknvpsqdel nkytdgmglp iypvgkypsn plglydmgls gsewtndwya
      121 edyyshspvk npqgpeqgtk kvlrgnvggd rqyaltmfrq sasplpeevd gdyekygvgp
      181 qyvfrcvvnk