ribose-phosphate diphosphokinase [Klebsiella pneumoniae].

LOCUS       WP_014343189             315 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_014343189
VERSION     WP_014343189.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 315)
  AUTHORS   Hove-Jensen,B., Andersen,K.R., Kilstrup,M., Martinussen,J.,
            Switzer,R.L. and Willemoes,M.
  TITLE     Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology,
            Utilization, and Metabolic Significance
  JOURNAL   Microbiol. Mol. Biol. Rev. 81 (1) (2016)
   PUBMED   28031352
REFERENCE   2  (residues 1 to 315)
  AUTHORS   Willemoes,M., Hove-Jensen,B. and Larsen,S.
  TITLE     Steady state kinetic model for the binding of substrates and
            allosteric effectors to Escherichia coli phosphoribosyl-diphosphate
            synthase
  JOURNAL   J. Biol. Chem. 275 (45), 35408-35412 (2000)
   PUBMED   10954724
REFERENCE   3  (residues 1 to 315)
  AUTHORS   Willemoes,M. and Hove-Jensen,B.
  TITLE     Binding of divalent magnesium by Escherichia coli phosphoribosyl
            diphosphate synthetase
  JOURNAL   Biochemistry 36 (16), 5078-5083 (1997)
   PUBMED   9125530
REFERENCE   4  (residues 1 to 315)
  AUTHORS   Hove-Jensen,B., Harlow,K.W., King,C.J. and Switzer,R.L.
  TITLE     Phosphoribosylpyrophosphate synthetase of Escherichia coli.
            Properties of the purified enzyme and primary structure of the prs
            gene
  JOURNAL   J. Biol. Chem. 261 (15), 6765-6771 (1986)
   PUBMED   3009477
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011247
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..315
                     /gene="prs"
     Protein         1..315
                     /product="ribose-phosphate diphosphokinase"
                     /EC_number="2.7.6.1"
                     /calculated_mol_wt=34135
     Region          4..314
                     /region_name="PRK01259"
                     /note="ribose-phosphate diphosphokinase"
                     /db_xref="CDD:234929"
ORIGIN      
        1 mpdmklfagn atpelaqria nrlytslgda avgrfsdgev svqinenvrg gdifiiqstc
       61 aptndnlmel vvmvdalrra sagritavip yfgyarqdrr vrsarvpita kvvadflssv
      121 gvdrvltvdl haeqiqgffd vpvdnvfgsp illedmlqln ldnpiavspd iggvvrarai
      181 akllndtdma iidkrrpran vsqvmhiigd vagrdcvmvd dmidtggtlc kaaealkerg
      241 akrvfayath pifsgnaiqn iknsvidefv vcdtiplape ikaldkvrtl tlsgmlaeai
      301 rrisneesis amfeh