Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

heme lyase CcmF/NrfE family subunit [Klebsiella pneumoniae].


LOCUS       WP_014343149             650 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_014343149
VERSION     WP_014343149.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 650)
  AUTHORS   Brausemann,A., Zhang,L., Ilcu,L. and Einsle,O.
  TITLE     Architecture of the membrane-bound cytochrome c heme lyase CcmF
  JOURNAL   Nat Chem Biol 17 (7), 800-805 (2021)
   PUBMED   33958791
REFERENCE   2  (residues 1 to 650)
  AUTHORS   Stevens,J.M., Mavridou,D.A., Hamer,R., Kritsiligkou,P.,
            Goddard,A.D. and Ferguson,S.J.
  TITLE     Cytochrome c biogenesis System I
  JOURNAL   FEBS J 278 (22), 4170-4178 (2011)
   PUBMED   21958041
REFERENCE   3  (residues 1 to 650)
  AUTHORS   Sanders,C., Turkarslan,S., Lee,D.W. and Daldal,F.
  TITLE     Cytochrome c biogenesis: the Ccm system
  JOURNAL   Trends Microbiol 18 (6), 266-274 (2010)
   PUBMED   20382024
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11439013
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..650
                     /product="heme lyase CcmF/NrfE family subunit"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015232 - heme transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /calculated_mol_wt=72167
     Region          2..649
                     /region_name="CcmF"
                     /note="Cytochrome c biogenesis protein CcmF [Energy
                     production and conversion, Posttranslational modification,
                     protein turnover, chaperones]; COG1138"
                     /db_xref="CDD:440753"
ORIGIN      
        1 mmpelgnfll claaglalll svyplwgaar qdrrlmalar placglfaci ggaflllvha
       61 fvvndftvry vaensnsalp vwyrvaatwg ahegslllwv lllsvwtfav aifsrrmsld
      121 avarvlavmg miafgfllfi lftsnpfsrg lpqypidgrd lnpllqdigm ifhppilymg
      181 yvgfsvafaf aiasllagrl dtawarwsrp wtqaawmflt lgivlgsawa yyelgwggww
      241 fwdpvenasf mpwlvgtall hslavtekrg sfrawtvlla iaafslcllg tflvrsgvlv
      301 svhafasdps rglfilvlli vaiggsllly alkggrvrar vehtlwsres fllgnnillm
      361 aamlvvllgt llplvhkelg lgsisigepf fntmftalma pfalllglgp lirwrrddva
      421 rqikrliial lvtlslslal pwllqdrita maviglmmal wvlifallev herathrhgf
      481 wrglraltrs qwgmvlghvg vavtvigitf sqnysverdv rmrpgdsidi hryhfvfngv
      541 rnivgpnwtg gegiiavtrn grpeatlyae krfytasrmm mteaaisggl trdlyaalge
      601 elsdgswavr lyykpfvrwi wyggvlmalg glccmldpry rmrkklqeas