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LOCUS WP_014343088 418 aa linear BCT 29-MAR-2023 [Klebsiella]. ACCESSION WP_014343088 VERSION WP_014343088.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 418) AUTHORS Hefti,M.H., Francoijs,K.J., de Vries,S.C., Dixon,R. and Vervoort,J. TITLE The PAS fold. A redefinition of the PAS domain based upon structural prediction JOURNAL Eur J Biochem 271 (6), 1198-1208 (2004) PUBMED 15009198 REFERENCE 2 (residues 1 to 418) AUTHORS Pei,J. and Grishin,N.V. TITLE GGDEF domain is homologous to adenylyl cyclase JOURNAL Proteins 42 (2), 210-216 (2001) PUBMED 11119645 REFERENCE 3 (residues 1 to 418) AUTHORS Ponting,C.P. and Aravind,L. TITLE PAS: a multifunctional domain family comes to light JOURNAL Curr Biol 7 (11), R674-R677 (1997) PUBMED 9382818 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 12140355 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..418 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..418 /product="sensor domain-containing diguanylate cyclase" /EC_number="2.7.7.65" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /GO_function="GO:0052621 - diguanylate cyclase activity [Evidence IEA]" /GO_process="GO:0007165 - signal transduction [Evidence IEA]" /calculated_mol_wt=47670 Region 8..>261 /region_name="KinE" /note="Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; COG5809" /db_xref="CDD:444511" Region 141..>262 /region_name="NtrB" /note="Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; COG3852" /db_xref="CDD:443061" Region <229..401 /region_name="GGDEF" /note="GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms]; COG2199" /db_xref="CDD:441801" ORIGIN 1 mllkelavfe vlstpiwvvh pfnervvyan qasrtlsgem slnemrngiy stcpetqlqh 61 ylryldtmse ifevwtlpta nglqsvyckt tlidtedcgc lllfeavkll aqnqsihtgs 121 rryqrrnngf farffmtnta pmllidphkd grivdaniaa lrfyhysdee mrtkhtwqin 181 tlgrdvipim nnianlpggh kplnfthila dgslrhvqty agpvvlynir lmlciihdit 241 eevhlkkele fsaahdpltg llnrrefhrl veaptfiprg yclllididh fksindihgh 301 qkgdevllvl sriletsvdr edkiyrwgge efllflphsp igralilaeg irqavseyqt 361 lsvtvsigva ehhdgetveq lfsrvdkaly aakndgrnrv srmpfdsser rrsrdgaa