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MULTISPECIES: sensor domain-containing diguanylate cyclase


LOCUS       WP_014343088             418 aa            linear   BCT 29-MAR-2023
            [Klebsiella].
ACCESSION   WP_014343088
VERSION     WP_014343088.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 418)
  AUTHORS   Hefti,M.H., Francoijs,K.J., de Vries,S.C., Dixon,R. and Vervoort,J.
  TITLE     The PAS fold. A redefinition of the PAS domain based upon
            structural prediction
  JOURNAL   Eur J Biochem 271 (6), 1198-1208 (2004)
   PUBMED   15009198
REFERENCE   2  (residues 1 to 418)
  AUTHORS   Pei,J. and Grishin,N.V.
  TITLE     GGDEF domain is homologous to adenylyl cyclase
  JOURNAL   Proteins 42 (2), 210-216 (2001)
   PUBMED   11119645
REFERENCE   3  (residues 1 to 418)
  AUTHORS   Ponting,C.P. and Aravind,L.
  TITLE     PAS: a multifunctional domain family comes to light
  JOURNAL   Curr Biol 7 (11), R674-R677 (1997)
   PUBMED   9382818
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 12140355
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..418
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=47670
     Region          8..>261
                     /region_name="KinE"
                     /note="Sporulation sensor histidine kinase E [Cell cycle
                     control, cell division, chromosome partitioning, Signal
                     transduction mechanisms]; COG5809"
                     /db_xref="CDD:444511"
     Region          141..>262
                     /region_name="NtrB"
                     /note="Signal transduction histidine kinase NtrB, nitrogen
                     specific [Signal transduction mechanisms]; COG3852"
                     /db_xref="CDD:443061"
     Region          <229..401
                     /region_name="GGDEF"
                     /note="GGDEF domain, diguanylate cyclase (c-di-GMP
                     synthetase) or its enzymatically inactive variants [Signal
                     transduction mechanisms]; COG2199"
                     /db_xref="CDD:441801"
ORIGIN      
        1 mllkelavfe vlstpiwvvh pfnervvyan qasrtlsgem slnemrngiy stcpetqlqh
       61 ylryldtmse ifevwtlpta nglqsvyckt tlidtedcgc lllfeavkll aqnqsihtgs
      121 rryqrrnngf farffmtnta pmllidphkd grivdaniaa lrfyhysdee mrtkhtwqin
      181 tlgrdvipim nnianlpggh kplnfthila dgslrhvqty agpvvlynir lmlciihdit
      241 eevhlkkele fsaahdpltg llnrrefhrl veaptfiprg yclllididh fksindihgh
      301 qkgdevllvl sriletsvdr edkiyrwgge efllflphsp igralilaeg irqavseyqt
      361 lsvtvsigva ehhdgetveq lfsrvdkaly aakndgrnrv srmpfdsser rrsrdgaa