MULTISPECIES: DHA2 family efflux MFS transporter permease subunit

LOCUS       WP_014343079             520 aa            linear   BCT 17-JUN-2024
            [Klebsiella].
ACCESSION   WP_014343079
VERSION     WP_014343079.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 520)
  AUTHORS   Colmer,J.A., Fralick,J.A. and Hamood,A.N.
  TITLE     Isolation and characterization of a putative multidrug resistance
            pump from Vibrio cholerae
  JOURNAL   Mol Microbiol 27 (1), 63-72 (1998)
   PUBMED   9466256
REFERENCE   2  (residues 1 to 520)
  AUTHORS   Lomovskaya,O. and Lewis,K.
  TITLE     Emr, an Escherichia coli locus for multidrug resistance
  JOURNAL   Proc Natl Acad Sci U S A 89 (19), 8938-8942 (1992)
   PUBMED   1409590
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00711.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..520
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=55960
     Region          21..504
                     /region_name="efflux_EmrB"
                     /note="drug resistance transporter, EmrB/QacA subfamily;
                     TIGR00711"
                     /db_xref="CDD:129794"
ORIGIN      
        1 mstvqalsap qglsmptakk ifafasmcvg mfialidiqi vsaslrdigg glsagddetv
       61 wvqtsyliae iiiiplsgwl arvmstrwlf aasaagftlm sllcgwawni qsmiafralq
      121 glaggsmipl vfttafaffq gkqrviaaat igglaslapt lgptvggwit enynwhwlff
      181 invvpgiyia vavpllvkvd sadptllrga dylsilllal slgcleytle egprwgwfdd
      241 atltttawva llcgvafvir tlrhpqpvmd lralqdrtfs lgcyfsfmag vgifatiylt
      301 plylgsvrgf saleiglavf stglfqvmsi pfyswlanrv dlrwllmagl igfavsmysf
      361 vpithdwgad qlllpqafrg laqqfavapt vtltlgslpp arlklasglf nlmrnlggai
      421 gialcgtvln drtnlhysrl adhlnnanla msdfvqrsaa nftvqgispd aaqtaalknl
      481 salalreart qafsdafyli mmgfllaall aplmkkppah