aldo/keto reductase, partial [Klebsiella pneumoniae].

LOCUS       WP_014343065             260 aa            linear   BCT 04-SEP-2024
ACCESSION   WP_014343065
VERSION     WP_014343065.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 260)
  AUTHORS   Gulbis,J.M., Zhou,M., Mann,S. and MacKinnon,R.
  TITLE     Structure of the cytoplasmic beta subunit-T1 assembly of
            voltage-dependent K+ channels
  JOURNAL   Science 289 (5476), 123-127 (2000)
   PUBMED   10884227
REFERENCE   2  (residues 1 to 260)
  AUTHORS   Wilson,D.K., Tarle,I., Petrash,J.M. and Quiocho,F.A.
  TITLE     Refined 1.8 A structure of human aldose reductase complexed with
            the potent inhibitor zopolrestat
  JOURNAL   Proc Natl Acad Sci U S A 90 (21), 9847-9851 (1993)
   PUBMED   8234324
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012472.5
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00248.26
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         <1..>260
                     /product="aldo/keto reductase"
     Region          <2..239
                     /region_name="AKR_SF"
                     /note="Aldo-keto reductase (AKR) superfamily; cl00470"
                     /db_xref="CDD:444925"
     Site            order(13,55,85..86,105,133..139,190,207..210,215,218..219)
                     /site_type="active"
                     /db_xref="CDD:381296"
ORIGIN      
        1 mapvrdrvvi atkfgfgvee gkptslnshp dhirravegs lkrlktdhid llyqhrpdpn
       61 vpiedvaetv kalilegkvk hwglseasar tirrahavlp vtavqseyam wwrepetrif
      121 ptleelgigf vpycptarsf lagavnpsqr fdstdrrhnl prfqpdalak nmvllefaqs
      181 warrknttpv qfalawvmaq rpwivpipgt tqyphliens gapqvrltdr elreidaala
      241 kiplqggrad pftesqfdks