trifunctional transcriptional regulator/proline

LOCUS       WP_014342987             986 aa            linear   BCT 10-DEC-2019
            dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
            [Klebsiella pneumoniae].
ACCESSION   WP_014342987
VERSION     WP_014342987.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 986)
  AUTHORS   Zhang,W., Zhou,Y. and Becker,D.F.
  TITLE     Regulation of PutA-membrane associations by flavin adenine
            dinucleotide reduction
  JOURNAL   Biochemistry 43 (41), 13165-13174 (2004)
   PUBMED   15476410
REFERENCE   2  (residues 1 to 986)
  AUTHORS   Zhang,M., White,T.A., Schuermann,J.P., Baban,B.A., Becker,D.F. and
            Tanner,J.J.
  TITLE     Structures of the Escherichia coli PutA proline dehydrogenase
            domain in complex with competitive inhibitors
  JOURNAL   Biochemistry 43 (39), 12539-12548 (2004)
   PUBMED   15449943
REFERENCE   3  (residues 1 to 986)
  AUTHORS   Gu,D., Zhou,Y., Kallhoff,V., Baban,B., Tanner,J.J. and Becker,D.F.
  TITLE     Identification and characterization of the DNA-binding domain of
            the multifunctional PutA flavoenzyme
  JOURNAL   J. Biol. Chem. 279 (30), 31171-31176 (2004)
   PUBMED   15155740
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008772.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11809
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..986
                     /gene="putA"
     Protein         1..986
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=108321
     Region          1..>907
                     /region_name="putA"
                     /note="trifunctional transcriptional regulator/proline
                     dehydrogenase/pyrroline-5-carboxylate dehydrogenase;
                     Reviewed; PRK11809"
                     /db_xref="CDD:236989"
ORIGIN      
        1 mgtttmgvkl ddatreriks aasridrtph wlikqaifny leklendetl pelpallsga
       61 anesddasep teepyqpfle faeqilpqsv sraaitaawr rpetdavpml leqarlpqpl
      121 geqahklayq laeklrnqkt asgragmvqs llqefslssq egvalmclae allripdkat
      181 rdalirdkis ngnwqshigr spslfvnaat wgllftgklv sthnetslsr slnriigksg
      241 eplirkgvdm amrlmgeqfv tgetiaeala narkleekgf rysydmlgea altaadaqay
      301 mvsyqqaiha igkasngrgi yegpgisikl salhprysra qydrvmeely prlksltlla
      361 rqydiginid aeeadrleis ldlleklcfe pelagwngig fviqayqkrc pfvidylidl
      421 atrsrrrlmi rlvkgaywds eikraqmegl egypvytrkv ytdvsylaca kkllavpnli
      481 ypqfathnah tlaaiyqlag qnyypgqyef qclhgmgepl yeqvvgkvad gklnrpcriy
      541 apvgthetll aylvrrllen gantsfvnri adntlpldel vadpvsavek laqqegqagl
      601 phpkiplprd lygsgrsnsa gldlanehrl aslsssllns alhkwqalpm leqpvaegem
      661 qpvvnpaepk divgyvreas daevqqalts ainnapiwfa tppqeraail eraavlmesq
      721 mptlmgilvr eagktfsnai aevreavdfl hyyagqvrdd fdnethrplg pvvcispwnf
      781 plaiftgqia aalaagnsvl akpaeqtpli aaqgvaille agvppgviql lpgrgetvga
      841 altsdervrg vmftgsteva tllqrniasr ldpqgrptpl iaetggmnam ivdssalteq
      901 vvidvlaprr qrrpallrpa ralpagrgrr shlnhaarrh ervpdgqsga pdhryrsgyr
      961 cgsereyrtp ysgdarqrph rlpgga