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tyrosine-type recombinase/integrase [Klebsiella pneumoniae].


LOCUS       WP_014342959             326 aa            linear   BCT 25-AUG-2024
ACCESSION   WP_014342959
VERSION     WP_014342959.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 326)
  AUTHORS   Guo,F., Gopaul,D.N. and van Duyne,G.D.
  TITLE     Structure of Cre recombinase complexed with DNA in a site-specific
            recombination synapse
  JOURNAL   Nature 389 (6646), 40-46 (1997)
   PUBMED   9288963
REFERENCE   2  (residues 1 to 326)
  AUTHORS   Kwon,H.J., Tirumalai,R., Landy,A. and Ellenberger,T.
  TITLE     Flexibility in DNA recombination: structure of the lambda integrase
            catalytic core
  JOURNAL   Science 276 (5309), 126-131 (1997)
   PUBMED   9082984
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012798.5
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00589.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..326
                     /product="tyrosine-type recombinase/integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=37203
     Region          2..309
                     /region_name="DNA_BRE_C"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain; cl00213"
                     /db_xref="CDD:469662"
     Site            order(156..157,160,175,178..179,212,214,216,262..263,
                     266..267,269..270,280,290,293)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271177"
     Site            order(183,257,260..261,292)
                     /site_type="active"
                     /db_xref="CDD:271177"
ORIGIN      
        1 mrkqfatkge alaferhtme eteakpwlge svdrrtlkdv velwfklhgk sltagqhvyd
       61 klllmvdalg nplatdltsk mfahyrdkrl tgeiyfsekw kkgaspvtin leqsylssvf
      121 selsrlgews ypnplenmrk ftiaekemaw ltheqivell adckrqdpil alvvkiclst
      181 garwreavnl trsqvtkyri tfvrtkgkkn rsipiskely eeimaldgfn fftdcyfqfl
      241 svmektsivl prgqlthvlr htfaahfmms ggnilalqki lghhdikmtm ryahlapdhl
      301 etalrfnpla tlprgdkvaa avgitp