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MULTISPECIES: LacI family DNA-binding transcriptional regulator


LOCUS       WP_014342939             316 aa            linear   BCT 13-MAY-2021
            [Klebsiella].
ACCESSION   WP_014342939
VERSION     WP_014342939.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10428550
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..316
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /calculated_mol_wt=34159
     Region          2..65
                     /region_name="HTH_XRE"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; cl22854"
                     /db_xref="CDD:473980"
     Site            order(7..11,13..14,17,22..23,26,39,42,45..46,48..49)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            39..48
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          56..314
                     /region_name="PBP1_LacI-like"
                     /note="ligand-binding domain of uncharacterized
                     DNA-binding regulatory proteins that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     cd06278"
                     /db_xref="CDD:380501"
     Site            order(67..68,71,115,138,151,187,259,276)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:380501"
     Site            order(68..70,73..74,76..77,84..88,90,100,103,106..108,211,
                     239,243,246..247)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:380501"
ORIGIN      
        1 marlagvsrs avsrtftpga svsektrqkv lsaaealgyq vniiartmit gssnfigivt
       61 agfdnpfrsk llaplvhqla lngfmpllmn addpqqlaps lkqllsyhva gviitsgapp
      121 lslaeeylar kipvtlinrh adlagcdrvc sdnaqgaklv adlfsrrgwr qvgfigenre
      181 nfstrqryea fiartsdmav ssrfcdsggy qagyqaarel vaenpgmqal fcatdmlalg
      241 aqdglrdaaa plpaivgfdd ipqadwqpyq lttvqqntal lahhavdllm triarfslps
      301 rhrevpvkli vrhsak