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PRD domain-containing protein [Klebsiella pneumoniae].


LOCUS       WP_014342933             703 aa            linear   BCT 02-MAR-2025
ACCESSION   WP_014342933
VERSION     WP_014342933.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 703)
  AUTHORS   Graille,M., Zhou,C.Z., Receveur-Brechot,V., Collinet,B.,
            Declerck,N. and van Tilbeurgh,H.
  TITLE     Activation of the LicT transcriptional antiterminator involves a
            domain swing/lock mechanism provoking massive structural changes
  JOURNAL   J Biol Chem 280 (15), 14780-14789 (2005)
   PUBMED   15699035
REFERENCE   2  (residues 1 to 703)
  AUTHORS   Declerck,N., Dutartre,H., Receveur,V., Dubois,V., Royer,C.,
            Aymerich,S. and van Tilbeurgh,H.
  TITLE     Dimer stabilization upon activation of the transcriptional
            antiterminator LicT
  JOURNAL   J Mol Biol 314 (4), 671-681 (2001)
   PUBMED   11733988
REFERENCE   3  (residues 1 to 703)
  AUTHORS   van Tilbeurgh,H. and Declerck,N.
  TITLE     Structural insights into the regulation of bacterial signalling
            proteins containing PRDs
  JOURNAL   Curr Opin Struct Biol 11 (6), 685-693 (2001)
   PUBMED   11751049
REFERENCE   4  (residues 1 to 703)
  AUTHORS   van Tilbeurgh,H., Le Coq,D. and Declerck,N.
  TITLE     Crystal structure of an activated form of the PTS regulation domain
            from the LicT transcriptional antiterminator
  JOURNAL   EMBO J 20 (14), 3789-3799 (2001)
   PUBMED   11447120
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013070.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00874.25
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..703
                     /product="PRD domain-containing protein"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=79588
     Region          <1..695
                     /region_name="LevR"
                     /note="Transcriptional regulatory protein LevR, contains
                     PRD, AAA+ and EIIA domains [Transcription]; COG3933"
                     /db_xref="CDD:443134"
ORIGIN      
        1 mlfidevhrl ppegqeklfh fmdngswrrl gesadersat vrlifasted lekhflatfi
       61 rripvivkil piaergqfer lafihhffrr eaqrlnhdla ldgeivsqlm retlegnvgg
      121 lenlirnica sawtfgerds gllhikagll pdrlladapf tlqqnservm iyrdgdaqpl
      181 fsgrhheyqr ltenicslce elaqdnisvr tfekliyqnv tlyldalmnq estvslqdkr
      241 lrfiedvgka iavnydlqln vefayltgry ltslplaprs vaepvrlvmq rwldssagla
      301 qriaeklldv vnnkydllid tldrlaitai vsnaidatsg gkvkaliiah gystassiag
      361 vanrligeki yqamdmpmev afndvsravv dylqhtdtra gvmvlidmgy tkeiadalls
      421 vingplvvvd nvttrmalnv aseialgkni eqiaeeivpl nqsrwdvfwp aekkervllv
      481 tcitgigtaf kfknlmeksl lndfdiniia ceytrlknsr tavsllhqye viavvgthdp
      541 qlagvpwvgi eellgeqghr hlsqllsgyl nekqialink nmvrefslhn vvnsltilna
      601 gktmghieti iaewqntlgf hfnnnliisl yvhlscmier lvmrneishy kdleqftrqh
      661 gefiamvnhs fqrlkilynv alpvaeigyi hdifelried fsw