aldehyde dehydrogenase family protein [Klebsiella pneumoniae].

LOCUS       WP_014342931             497 aa            linear   BCT 02-MAR-2025
ACCESSION   WP_014342931
VERSION     WP_014342931.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 497)
  AUTHORS   Steinmetz,C.G., Xie,P., Weiner,H. and Hurley,T.D.
  TITLE     Structure of mitochondrial aldehyde dehydrogenase: the genetic
            component of ethanol aversion
  JOURNAL   Structure 5 (5), 701-711 (1997)
   PUBMED   9195888
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012398.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00171.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..497
                     /product="aldehyde dehydrogenase family protein"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=53257
     Region          22..497
                     /region_name="ALDH-SF"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; cl11961"
                     /db_xref="CDD:448367"
     Site            order(168..172,180,195,197..198,246..249,252,255..256,
                     270..272,304,401,403,429,467)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143431"
     Site            order(172,270,301,304)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143431"
ORIGIN      
        1 mltmseitll aevtaflrqp hgqfiagqre agrgapfavi npatgraiae vtaadsdqad
       61 ramesarqaf sqwremptla rgalllklad tlaehreala qleslcsgkt itlarmleld
      121 qsvaflryfa gwagkvtget ldvslpsmag ekytaftrrq plgvvvgivp wnfsimiaiw
      181 klaaalvcgc tivlkpseyt pltllrvael akavgipdgv invvngagge iaqrlithpa
      241 cakvsftgsv atgekvqqsa sasgkrvtle lggknaalfl ddltpeamvn giieagylnq
      301 gqicaaaerf ylpqgkldav lallkdklsa fapgsplder tlmgplanrq qydkvlrliq
      361 tardegdtiv cggealpgeg yflqptavkv rseestlmre etfgpvcsfi gyrseeeala
      421 rinaspygla asvwsdnirq alryseaiea givwvnmhtf ldpavpfggm kgsgigrefg
      481 safiddytel ksvmvry