EAL domain-containing protein [Klebsiella pneumoniae].

LOCUS       WP_014342882             513 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_014342882
VERSION     WP_014342882.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 513)
  AUTHORS   Simm,R., Morr,M., Kader,A., Nimtz,M. and Romling,U.
  TITLE     GGDEF and EAL domains inversely regulate cyclic di-GMP levels and
            transition from sessility to motility
  JOURNAL   Mol Microbiol 53 (4), 1123-1134 (2004)
   PUBMED   15306016
REFERENCE   2  (residues 1 to 513)
  AUTHORS   D'Argenio,D.A. and Miller,S.I.
  TITLE     Cyclic di-GMP as a bacterial second messenger
  JOURNAL   Microbiology (Reading) 150 (Pt 8), 2497-2502 (2004)
   PUBMED   15289546
REFERENCE   3  (residues 1 to 513)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11471819
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..513
                     /product="EAL domain-containing protein"
                     /EC_number="3.1.4.52"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=58414
     Region          1..513
                     /region_name="YjcC"
                     /note="Redox-sensing c-di-GMP phosphodiesterase, contains
                     CSS-motif and EAL domains [Signal transduction
                     mechanisms]; COG4943"
                     /db_xref="CDD:443970"
ORIGIN      
        1 malftgvlil aiilpislsi wqaarqakmq fyrelddysn rivvrtlqva dqarealrea
       61 dahtaascsp ehlltlrria ythryiqevl wlrdsvpqcs sledhsvavt fpppdhiapd
      121 gyrtwltsin dlgldhqmta mgsrqhmvmi dpvsfidvvp aseekihtml fgldhqkmvi
      181 ssqplpakvw qrikdphvdm ltldntvyri qripelgsgi vtwsstlplq qrirqqlffw
      241 lpagiftsll atwlllrllr hlrsprnsml dalnseaiqv yyqpiislqd gkiagaeala
      301 rwqqpdgtfl spdifiplae qtglitqlte divrkiftdl gpwlrqrpev hisinlsvdd
      361 lrsptlptll hdqlqhwgia aeqiileite rgfvdpettm pviahyrqag hrisiddfgt
      421 gysslsylqk ldvdtlkidk sfvdtleyrp ltphiiemak alnlatvaeg vetesqrdwl
      481 rqhgvqyaqg wlyskalpke qfilwaehnl hah