glutarate dioxygenase GlaH [Salmonella enterica].

LOCUS       WP_012664661             328 aa            linear   BCT 30-MAY-2022
ACCESSION   WP_012664661
VERSION     WP_012664661.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 328)
  AUTHORS   Knorr,S., Sinn,M., Galetskiy,D., Williams,R.M., Wang,C., Muller,N.,
            Mayans,O., Schleheck,D. and Hartig,J.S.
  TITLE     Widespread bacterial lysine degradation proceeding via glutarate
            and L-2-hydroxyglutarate
  JOURNAL   Nat Commun 9 (1), 5071 (2018)
   PUBMED   30498244
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 328)
  AUTHORS   Marschall,C., Labrousse,V., Kreimer,M., Weichart,D., Kolb,A. and
            Hengge-Aronis,R.
  TITLE     Molecular analysis of the regulation of csiD, a carbon
            starvation-inducible gene in Escherichia coli that is exclusively
            dependent on sigma s and requires activation by cAMP-CRP
  JOURNAL   J Mol Biol 276 (2), 339-353 (1998)
   PUBMED   9512707
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002814.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02963
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     gene            1..328
                     /gene="glaH"
     Protein         1..328
                     /product="glutarate dioxygenase GlaH"
                     /EC_number="1.14.11.64"
                     /GO_function="GO:0050498 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, with 2-oxoglutarate as one donor, and
                     the other dehydrogenated [Evidence IEA]"
                     /calculated_mol_wt=37460
     Region          10..325
                     /region_name="PRK02963"
                     /note="carbon starvation induced protein CsiD"
                     /db_xref="CDD:235092"
     Site            order(133,166,168,173,220,312,314)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238154"
     Site            order(163,165,191,295,308)
                     /site_type="active"
                     /db_xref="CDD:238154"
     Site            order(163,165,295)
                     /site_type="other"
                     /note="iron coordination sites [ion binding]"
                     /db_xref="CDD:238154"
ORIGIN      
        1 milmnaltav kantddlaqr htgftlapsa qsprllaltf tadttkqflh qvaqwpvqal
       61 eyksflrfki gkilddlcgn qlqplliktl lnraqgalli saegiddvaq aeemvklata
      121 vahligrsny damsgqyyar fvvknvdnsd sylrqphrvm elhndgtyve evtdyvlmmk
      181 ideqnmeggn slllhlddwe hlesffthpl arrvmrwaap psknvshdvw hpvfdvdqqg
      241 rpvmryidqf vqpkdfeegv wlselsdale tsqnilsvpv pvgkfllinn lfwlhgrdrf
      301 tphpdlrrel mrqrgyfaya ashyqthq