MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_012543325             412 aa            linear   BCT 22-JUL-2024
ACCESSION   WP_012543325
VERSION     WP_012543325.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 412)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 412)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..412
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=44757
     Region          18..390
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(28..29,32..33,36,68,118..119,121..123,126,146,
                     149..150,153,228,231..232,235..237,240,268,272,321..322,
                     326,330,345,348..349,352..353,356)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mcmknnieet igkylpilmi lplaglaela slysiqallp klsevynipl nqvgmilsae
       61 vgflalamlf sgtlsdrfgr kpiifyslla ggiltllcat asswpmlvvy rallgiavsg
      121 itaavtvyis eevspalagi vtgyfifgns lgsmsgrvfa tlmmehvsid tiffifggvl
      181 iamalavklf lptsrqfvpt pslqlgavlk gglehfknir vslcfvigfi lfgsftsifn
      241 flafylhrpp yelsytwigl ipvsfsltff lapyaarval nigsmnalsm liicmmvgaf
      301 ltliapslwv fisgivllsv affsahstvl awvssrspna kgqatsfyll cyysggavmg
      361 ylngylfswq gwnaiaascl mmlgiglfic rfifakyekq pqikkqsvqe sf