carbonate dehydratase [Klebsiella pneumoniae].

LOCUS       WP_011977664             204 aa            linear   BCT 04-JUL-2022
ACCESSION   WP_011977664
VERSION     WP_011977664.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 204)
  AUTHORS   Langereis,J.D., Zomer,A., Stunnenberg,H.G., Burghout,P. and
            Hermans,P.W.
  TITLE     Nontypeable Haemophilus influenzae carbonic anhydrase is important
            for environmental and intracellular survival
  JOURNAL   J Bacteriol 195 (12), 2737-2746 (2013)
   PUBMED   23564172
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007756.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10437
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..204
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..204
                     /gene="can"
     Protein         1..204
                     /product="carbonate dehydratase"
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /calculated_mol_wt=23224
     Region          1..204
                     /region_name="beta_CA"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; cl00391"
                     /db_xref="CDD:469755"
     Site            order(17,19,26,28..30,42,45,67,72,82,85,165)
                     /site_type="active"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238448"
     Site            order(26,28,82,85)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238448"
     Site            order(27..30,32,34..35,37,42..44,46,48,62..63,66..67,103,
                     165,167..168,170,172)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238448"
ORIGIN      
        1 mlveedpgff eklsqtqkpr flwigcsdsr vpaerltgle pgelfvhrnv anlvihtdln
       61 clsvvqyavd vlevehiiic ghygcggvqa avenpelgli dnwllhirdi wfkhssllge
      121 mpeerrldtl celnvmeqvy nlghstimqs awkrgqkvti hgwaygihdg llrdldvtav
      181 sretleqryr hgisnlkikh inhr