Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

two-component system sensor histidine kinase EnvZ [Photobacterium


LOCUS       WP_011217002             443 aa            linear   BCT 17-OCT-2022
            profundum].
ACCESSION   WP_011217002
VERSION     WP_011217002.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium profundum
  ORGANISM  Photobacterium profundum
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 443)
  AUTHORS   Reboul,A., Lemaitre,N., Titecat,M., Merchez,M., Deloison,G.,
            Ricard,I., Pradel,E., Marceau,M. and Sebbane,F.
  TITLE     Yersinia pestis requires the 2-component regulatory system
            OmpR-EnvZ to resist innate immunity during the early and late
            stages of plague
  JOURNAL   J Infect Dis 210 (9), 1367-1375 (2014)
   PUBMED   24813471
REFERENCE   2  (residues 1 to 443)
  AUTHORS   Tomomori,C., Tanaka,T., Dutta,R., Park,H., Saha,S.K., Zhu,Y.,
            Ishima,R., Liu,D., Tong,K.I., Kurokawa,H., Qian,H., Inouye,M. and
            Ikura,M.
  TITLE     Solution structure of the homodimeric core domain of Escherichia
            coli histidine kinase EnvZ
  JOURNAL   Nat Struct Biol 6 (8), 729-734 (1999)
   PUBMED   10426948
REFERENCE   3  (residues 1 to 443)
  AUTHORS   Tanaka,T., Saha,S.K., Tomomori,C., Ishima,R., Liu,D., Tong,K.I.,
            Park,H., Dutta,R., Qin,L., Swindells,M.B., Yamazaki,T., Ono,A.M.,
            Kainosho,M., Inouye,M. and Ikura,M.
  TITLE     NMR structure of the histidine kinase domain of the E. coli
            osmosensor EnvZ
  JOURNAL   Nature 396 (6706), 88-92 (1998)
   PUBMED   9817206
REFERENCE   4  (residues 1 to 443)
  AUTHORS   Yaku,H. and Mizuno,T.
  TITLE     The membrane-located osmosensory kinase, EnvZ, that contains a
            leucine zipper-like motif functions as a dimer in Escherichia coli
  JOURNAL   FEBS Lett 417 (3), 409-413 (1997)
   PUBMED   9409762
REFERENCE   5  (residues 1 to 443)
  AUTHORS   Forst,S., Comeau,D., Norioka,S. and Inouye,M.
  TITLE     Localization and membrane topology of EnvZ, a protein involved in
            osmoregulation of OmpF and OmpC in Escherichia coli
  JOURNAL   J Biol Chem 262 (34), 16433-16438 (1987)
   PUBMED   2824492
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007004.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09467
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Photobacterium profundum"
                     /db_xref="taxon:74109"
     gene            1..443
                     /gene="envZ"
     Protein         1..443
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /EC_number="2.7.13.3"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /calculated_mol_wt=49461
     Region          1..442
                     /region_name="envZ"
                     /note="osmolarity sensor protein; Provisional; PRK09467"
                     /db_xref="CDD:236531"
ORIGIN      
        1 mrfsprstft rtlvllsgll iasqifsylt vinyallpsl qqfnriiaye vrlmlqedld
       61 ldlddgevfh leqpvrrqll aqlgvtlhsv ddpdlkeynr ateieylsde mseeldakte
      121 vrlvlgaesy vlwmkcdamp gylmriplse lqeedfaplf rysliiafmv iaggwlfirm
      181 qnrplveler aallvargei pptlpeqgas evravtkafn qmaegmkqle ddralllagv
      241 shdlrtpltr irlatemmsp edsyladgmt kdteecneii sqfmdylkst kkpvmdvidl
      301 ndllqevaes eggyenevel glsdtpgrie anavamkrcv anlvvnalry gngwvkissg
      361 tsadrksawy cvedngpgiq edqvsrmfqp ltrgdsargs daegtglgla ivkriidqhd
      421 gvitvtnrrd gglkvqitls lvk