cation:proton antiporter [Vibrio vulnificus].

LOCUS       WP_011151259             444 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_011151259
VERSION     WP_011151259.1
KEYWORDS    RefSeq.
SOURCE      Vibrio vulnificus
  ORGANISM  Vibrio vulnificus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 444)
  AUTHORS   Malo,M.E. and Fliegel,L.
  TITLE     Physiological role and regulation of the Na+/H+ exchanger
  JOURNAL   Can J Physiol Pharmacol 84 (11), 1081-1095 (2006)
   PUBMED   17218973
REFERENCE   2  (residues 1 to 444)
  AUTHORS   Alexander,R.T. and Grinstein,S.
  TITLE     Na+/H+ exchangers and the regulation of volume
  JOURNAL   Acta Physiol (Oxf) 187 (1-2), 159-167 (2006)
   PUBMED   16734752
REFERENCE   3  (residues 1 to 444)
  AUTHORS   Hayashi,H., Szaszi,K. and Grinstein,S.
  TITLE     Multiple modes of regulation of Na+/H+ exchangers
  JOURNAL   Ann N Y Acad Sci 976, 248-258 (2002)
   PUBMED   12502567
REFERENCE   4  (residues 1 to 444)
  AUTHORS   Burckhardt,G., Di Sole,F. and Helmle-Kolb,C.
  TITLE     The Na+/H+ exchanger gene family
  JOURNAL   J Nephrol 15 Suppl 5, S3-S21 (2002)
   PUBMED   12027219
REFERENCE   5  (residues 1 to 444)
  AUTHORS   Dibrov,P. and Fliegel,L.
  TITLE     Comparative molecular analysis of Na+/H+ exchangers: a unified
            model for Na+/H+ antiport?
  JOURNAL   FEBS Lett 424 (1-2), 1-5 (1998)
   PUBMED   9537504
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10000258
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Vibrio vulnificus"
                     /db_xref="taxon:672"
     Protein         1..444
                     /product="cation:proton antiporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015078 - proton transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48682
     Region          1..>429
                     /region_name="NhaP"
                     /note="NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion
                     transport and metabolism]; COG0025"
                     /db_xref="CDD:439796"
ORIGIN      
        1 msvyytlcfl saaamliafv nskigkmqtt iaitagsmvl slliliagqn nwfhlteiat
       61 qtmssidfed fllkgilgfl lfagglgikl pnlkdqkwei tvlalgatlf stffigfaly
      121 gicqligiqf dliycllfga lisptdpiav laivkklkap rristqiege slfndgfglv
      181 ifvtlftiaf ghetptvgsv tmlfiqeaig gilygfalgl lfhylicatd dhsmelllti
      241 giptagyafa evlhvsgpla mvvsgimign wtrfigfske sedhldhfwe lvdeflngvl
      301 flligmsmll fkfhqedwil maiaiplvli arylsvflsy igfkrfrqyn pwsikiltwg
      361 glrgglalam alsipsgiwv ipdklidvke iilvmtyavv vfsilvqgst itpmiekakq
      421 seaefeakqs svtapegkte siss