1-deoxy-D-xylulose-5-phosphate reductoisomerase [Vibrio

LOCUS       WP_011079768             402 aa            linear   BCT 28-MAR-2022
            vulnificus].
ACCESSION   WP_011079768
VERSION     WP_011079768.1
KEYWORDS    RefSeq.
SOURCE      Vibrio vulnificus
  ORGANISM  Vibrio vulnificus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 402)
  AUTHORS   Haymond,A., Johny,C., Dowdy,T., Schweibenz,B., Villarroel,K.,
            Young,R., Mantooth,C.J., Patel,T., Bases,J., San Jose,G.,
            Jackson,E.R., Dowd,C.S. and Couch,R.D.
  TITLE     Kinetic characterization and allosteric inhibition of the Yersinia
            pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP
            synthase)
  JOURNAL   PLoS One 9 (8), e106243 (2014)
   PUBMED   25171339
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003938.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05447
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Vibrio vulnificus"
                     /db_xref="taxon:672"
     gene            1..402
                     /gene="ispC"
     Protein         1..402
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /EC_number="1.1.1.267"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=43221
     Region          1..401
                     /region_name="Dxr"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase
                     [Lipid transport and metabolism]; COG0743"
                     /db_xref="CDD:440506"
ORIGIN      
        1 mqkltilgat gsigastlkv ieqnpdkfsv valaadsnve kmqqlcqrwq peyavmanke
       61 aalrlkmala vlapntqvlg gqealcyvat leqvdsvmaa ivgaaglvpt maavkagkri
      121 llankealvm sgqlfideve ksgaqllpvd sehnaifqcl pqtvqgnlgr cdlasqgvsh
      181 illtgsggpf rytdvaelea vtpeqaiahp nwsmgpkisv dsatmmnkgl eyieakwlfn
      241 asrdqlkvii hpqsvihsmv qyldgsvlaq mgepdmatpi altlsyperv kagvkpldft
      301 qvgeltflqp dferypclal aieacylgqh atttlnaane vavaaflarq ikftdiarvn
      361 dsvlnqvckq slasgldsle slleldrmar tladevvrer aq