M48 family metallopeptidase [Shigella flexneri].

LOCUS       WP_011069500             294 aa            linear   BCT 21-MAR-2023
ACCESSION   WP_011069500
VERSION     WP_011069500.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 294)
  AUTHORS   Soltes,G.R., Martin,N.R., Park,E., Sutterlin,H.A. and Silhavy,T.J.
  TITLE     Distinctive Roles for Periplasmic Proteases in the Maintenance of
            Essential Outer Membrane Protein Assembly
  JOURNAL   J Bacteriol 199 (20), e00418-17 (2017)
   PUBMED   28784813
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11574521
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..294
                     /product="M48 family metallopeptidase"
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=31600
     Region          72..287
                     /region_name="M48C_loiP_like"
                     /note="Peptidase M48C Ste24p loiP-like, integral membrane
                     protein; cd07334"
                     /db_xref="CDD:320693"
     Site            order(172..173,176,231,235,274)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:320693"
     Site            order(172,176,231,274)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:320693"
ORIGIN      
        1 mlaccaicsp vrcafpytet errftckrri friiltlcgr enmkirallv amsvatvltg
       61 cqnmdsngll ssgaeafqay slsdaqvktl sdqacqemds katiapanse yakrlttian
      121 algnningqp vnykvymakd vnafamangc irvysglmdm mtdneveavi ghemghvalg
      181 hvkkgmqval gtnavrvaaa saggivgsls qsqlgdlgek lvnsqfsqrq eaeaddysyd
      241 llhqrgispa glatsfekla kleegrqssm fddhpasaer aqhirdrisa dgik