class 1b ribonucleoside-diphosphate reductase subunit alpha

LOCUS       WP_011069481             701 aa            linear   BCT 19-JUN-2019
            [Shigella flexneri].
ACCESSION   WP_011069481
VERSION     WP_011069481.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 701)
  AUTHORS   Zhang,Y. and Stubbe,J.
  TITLE     Bacillus subtilis class Ib ribonucleotide reductase is a
            dimanganese(III)-tyrosyl radical enzyme
  JOURNAL   Biochemistry 50 (25), 5615-5623 (2011)
   PUBMED   21561096
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..701
                     /gene="nrdE"
     Protein         1..701
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /calculated_mol_wt=78984
     Region          2..701
                     /region_name="RNR_1b_NrdE"
                     /note="ribonucleoside-diphosphate reductase, class 1b,
                     alpha subunit; TIGR04170"
                     /db_xref="CDD:211905"
ORIGIN      
        1 mdyhalnaml nlydsagriq fdkdrqavda fiathvrpns vtfssqqqrl nwlvnegyyd
       61 esvlnrysrd fvitlfahah tsgfrfqtfl gawkfytsyt lktfdgkryl edfadrvtmv
      121 altlaqgdet lalqltdeml sgrfqpatpt flncgkqqrg elvscfllri ednmesigra
      181 vnsalqlskr gggvafllsn lreagapikr ienqssgvip vmkmledafs yanqlgarqg
      241 agavylhahh pdilrfldtk renadekiri ktlslgvvip ditfhlaken aqmalfspyd
      301 vervygkpfa diaisehyde lvaderirkk ylnardffqr laeiqfesgy pyimyedtvn
      361 ranpiagrin msnlcseilq vnsaseyden ldyartghdi scnlgslnia htmdspdfsr
      421 tvetavrglt avsdmshirs vpsieagnaa shaiglgqmn lhgylaregi aygspealdf
      481 tnlyfytitw halrtsmlla rergetfagf kqsryasgey fsqylqgnwq pktakvgelf
      541 arscitlptr emwaqlrddv mrygiynqnl qavpptgsis yinhatssih pivakveirk
      601 egktgrvyyp apfmtnenla lyqdayeiga ekiidtyaea trhvdqglsl tlffpdtatt
      661 rdinkaqiya wrkgiktlyy irlrqmaleg teiegcvsca l