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LOCUS WP_011069436 732 aa linear BCT 11-DEC-2019 ACCESSION WP_011069436 VERSION WP_011069436.1 KEYWORDS RefSeq. SOURCE Shigella flexneri ORGANISM Shigella flexneri Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 732) AUTHORS Collins,R.F., Beis,K., Dong,C., Botting,C.H., McDonnell,C., Ford,R.C., Clarke,B.R., Whitfield,C. and Naismith,J.H. TITLE The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli JOURNAL Proc. Natl. Acad. Sci. U.S.A. 104 (7), 2390-2395 (2007) PUBMED 17283336 REFERENCE 2 (residues 1 to 732) AUTHORS Grangeasse,C., Obadia,B., Mijakovic,I., Deutscher,J., Cozzone,A.J. and Doublet,P. TITLE Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase JOURNAL J. Biol. Chem. 278 (41), 39323-39329 (2003) PUBMED 12851388 REFERENCE 3 (residues 1 to 732) AUTHORS Nakar,D. and Gutnick,D.L. TITLE Involvement of a protein tyrosine kinase in production of the polymeric bioemulsifier emulsan from the oil-degrading strain Acinetobacter lwoffii RAG-1 JOURNAL J. Bacteriol. 185 (3), 1001-1009 (2003) PUBMED 12533476 REFERENCE 4 (residues 1 to 732) AUTHORS Paiment,A., Hocking,J. and Whitfield,C. TITLE Impact of phosphorylation of specific residues in the tyrosine autokinase, Wzc, on its activity in assembly of group 1 capsules in Escherichia coli JOURNAL J. Bacteriol. 184 (23), 6437-6447 (2002) PUBMED 12426330 REFERENCE 5 (residues 1 to 732) AUTHORS Doublet,P., Grangeasse,C., Obadia,B., Vaganay,E. and Cozzone,A.J. TITLE Structural organization of the protein-tyrosine autokinase Wzc within Escherichia coli cells JOURNAL J. Biol. Chem. 277 (40), 37339-37348 (2002) PUBMED 12138098 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF008568.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK11519 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..732 /organism="Shigella flexneri" /db_xref="taxon:623" gene 1..732 /gene="wzc" Protein 1..732 /product="tyrosine-protein kinase Wzc" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_process="GO:0009103 - lipopolysaccharide biosynthetic process [Evidence IEA]" /calculated_mol_wt=80576 Region 13..731 /region_name="PRK11519" /note="tyrosine-protein kinase Wzc" /db_xref="CDD:183173" Site order(520,523..524,526..528,548,576,578..579,621,630,633, 656..657,659..662,665..666,669,681..682,684,686..687,690, 694,697..698) /site_type="other" /note="oligomer interface [polypeptide binding]" /db_xref="CDD:349772" Site order(549..554,576,581,654,708) /site_type="active" /db_xref="CDD:349772" ORIGIN 1 mgagierrag irmtekvkqh aapvtgsdei digrlvgtvi earwwvigit vvfalcavvy 61 tffatpiysa dalvqieqns gnslvqdigs alankppasd aeiqlirsrl vlgktvddld 121 ldiavskntf pifgagwdrl mgrqnetvkv ttfnrpkema dqvftlnvld dknytlssdg 181 gfsargqagq mlkkegvtlm veaiharpgs eftvtkystl gminqlqnsl tvtengkdag 241 vlsltytged reqirdilns iarnyqeqni erksaeasks laflaqqlpe vrsrldvaen 301 klnafrqdkd svdlpleaka vldsmvnida qlneltfkea eisklytkvh payrtllekr 361 qaleeekakl ngrvtampkn qqeivrltrd vesgqqvymq llnkeqelki teastvgdvr 421 iidpaitqpg vlkpkkglii lgaiilglml sivgvllrsl fnrgiespqv leehgisvya 481 siplsewqka rdsvktikgv krykqsqlla vgnptdlaie airslrtslh fammqaqnnv 541 lmmtgvspsi gktfvcanla avisqtnkrv llidcdmrkg ythellgtnn vnglseilig 601 qgdittaakp tsiakfdlip rgqvppnpse llmserfael vnwasknydl vlidtppila 661 vtdaaivgrh vgttlmvary avntlkevet slsrfeqngi pvkgvilnsi frrasayqdy 721 gyyeyeyksd ak