MULTISPECIES: DHA2 family efflux MFS transporter permease subunit

LOCUS       WP_011069405             484 aa            linear   BCT 17-JUN-2024
            [Shigella].
ACCESSION   WP_011069405
VERSION     WP_011069405.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 484)
  AUTHORS   Colmer,J.A., Fralick,J.A. and Hamood,A.N.
  TITLE     Isolation and characterization of a putative multidrug resistance
            pump from Vibrio cholerae
  JOURNAL   Mol Microbiol 27 (1), 63-72 (1998)
   PUBMED   9466256
REFERENCE   2  (residues 1 to 484)
  AUTHORS   Lomovskaya,O. and Lewis,K.
  TITLE     Emr, an Escherichia coli locus for multidrug resistance
  JOURNAL   Proc Natl Acad Sci U S A 89 (19), 8938-8942 (1992)
   PUBMED   1409590
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00711.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..484
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=53378
     Region          8..483
                     /region_name="efflux_EmrB"
                     /note="drug resistance transporter, EmrB/QacA subfamily;
                     TIGR00711"
                     /db_xref="CDD:129794"
ORIGIN      
        1 mmsmrkhiaf asmcmglfia qldiqivsss lneiggglsa gkdemawlqt syliaeiivi
       61 plsgwlsrvf strwlftlsa giftlmsiac glawniqimi lfralqgaag asmiplvftm
      121 afiyyqgkel glaaavvsal aslsptlgpt lggwltdnld wrwlfyinil pgiylvlsip
      181 flvnfdkpdl sllkvadyps iillamtlgc leytleegar wgwlddntil ltsvlalvsf
      241 ilfaartlti snpimdlhaf kdknftlgcf fsfsggvgif stvylipvfl gqirglnaee
      301 igfavcttgi fqlfsvpfyf wlskkinlrw llmaglggfv fsmylftpit hewgwqellf
      361 pqairgisqq famapivtlt lggipkerlk lasgvfnltr nlggaigial cgsilnnrtn
      421 fhfsrmgekm vsvphtvndf isrsalffnr srsdqtseil astkllsqlm lreaqtmafs
      481 vpfc