NADP-dependent oxidoreductase [Shigella flexneri].

LOCUS       WP_011069396             398 aa            linear   BCT 24-JUL-2024
ACCESSION   WP_011069396
VERSION     WP_011069396.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 398)
  AUTHORS   Persson,B., Hedlund,J. and Jornvall,H.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the MDR superfamily
  JOURNAL   Cell Mol Life Sci 65 (24), 3879-3894 (2008)
   PUBMED   19011751
REFERENCE   2  (residues 1 to 398)
  AUTHORS   Nordling,E., Jornvall,H. and Persson,B.
  TITLE     Medium-chain dehydrogenases/reductases (MDR). Family
            characterizations including genome comparisons and active site
            modeling
  JOURNAL   Eur J Biochem 269 (17), 4267-4276 (2002)
   PUBMED   12199705
REFERENCE   3  (residues 1 to 398)
  AUTHORS   Lesk,A.M.
  TITLE     NAD-binding domains of dehydrogenases
  JOURNAL   Curr Opin Struct Biol 5 (6), 775-783 (1995)
   PUBMED   8749365
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11450230
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..398
                     /product="NADP-dependent oxidoreductase"
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /calculated_mol_wt=43412
     Region          39..372
                     /region_name="CurA"
                     /note="NADPH-dependent curcumin reductase CurA [Secondary
                     metabolites biosynthesis, transport and catabolism,
                     General function prediction only]; COG2130"
                     /db_xref="CDD:441733"
ORIGIN      
        1 mlqrgcdgck qnqsrepati dgfmpkaqes imgqqkqrnr rwvlpsrphg apvpenfrle
       61 eddvatpgeg qvllrtvyls ldpymrgrms depsysppvd iggvmvggtv srvvesnhpd
      121 yqpgdwvlgy sgwqdydiss gddlvklgdh pqnpswslgv lgmpgftaym glldigqpke
      181 getlvvaaat epvgatvgqi gklkgcrvvg vaggaekcrh atevlgfdvc ldhhaddfae
      241 qlakacpkgi diyyenvggk vfdavlplln tsaripvcgl vssynatelp pgpdrlpllm
      301 atvlkkrirl qgfiiaqdyg hrihefqkem gqwvkedkih yreditdgle napqtfigll
      361 kgknfgkvvi rvagddksfn ggvsrhknpg kklifsfn