bifunctional NADP-dependent 3-hydroxy acid

LOCUS       WP_011069376             248 aa            linear   BCT 02-JUN-2019
            dehydrogenase/3-hydroxypropionate dehydrogenase YdfG [Shigella
            flexneri].
ACCESSION   WP_011069376
VERSION     WP_011069376.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007829.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10538
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..248
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..248
                     /gene="ydfG"
     Protein         1..248
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=27105
     Region          1..248
                     /region_name="PRK10538"
                     /note="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /db_xref="CDD:182531"
     Site            order(7,9..12,31..33,53..55,81..83,105,132..134,147,151,
                     177..180,183..184)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187604"
     Site            order(58,90..91,96..97,99..100,103..104,107..108,111..112,
                     115,118,122,136..146,148..150,152..153,156..157,160..161,
                     163..164,166..167,246)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187604"
     Site            order(58,91,96..97,99..100,104,108,112,115,137..140,
                     142..145,149..150,152..153,156,159..160,162..164,211,218,
                     225,227,229..246)
                     /site_type="other"
                     /note="homotetramer interface [polypeptide binding]"
                     /db_xref="CDD:187604"
     Site            order(106,134,147,151)
                     /site_type="active"
                     /db_xref="CDD:187604"
ORIGIN      
        1 mivlvtgata gfgecitrrf iqqghkviat grrqerlqel tdelgdnlyi aqldvrnraa
       61 ieemlaslpa ewsnidilvn naglalgmep ahkasvedwe tmidtnnkgl vymtravlpg
      121 mvernhghii nigstagswp yaggnvygat kafvrqfsln lrtdlhgttv rvtdiepglv
      181 ggtefsnvrf kgddgkaekt yqntvaltpe dvseavwwvs tlpahvnint lemmpvtqsy
      241 aglnvhrq