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3-isopropylmalate dehydrogenase [Shigella flexneri].


LOCUS       WP_011069243             364 aa            linear   BCT 19-JUN-2019
ACCESSION   WP_011069243
VERSION     WP_011069243.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 364)
  AUTHORS   Dean,A.M. and Golding,G.B.
  TITLE     Protein engineering reveals ancient adaptive replacements in
            isocitrate dehydrogenase
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3104-3109 (1997)
   PUBMED   9096353
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00169.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..364
                     /gene="leuB"
     Protein         1..364
                     /product="3-isopropylmalate dehydrogenase"
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39515
     Region          4..363
                     /region_name="PRK00772"
                     /note="3-isopropylmalate dehydrogenase; Provisional"
                     /db_xref="CDD:234832"
ORIGIN      
        1 mmsknyhiav lpgdgigpev mtqalkvlna vrnrfamrit tshydvggaa idnhgqplpp
       61 atvegceqad avlfgsvggp kwehlppdqq pergallplr khfklfsnlr paklyqglea
      121 fcplradiaa ngfdiqcvre ltggiyfgqp kgregsgqye kafdtevyhr feieriaria
      181 fesarkrrhk vtsidkanvl qssilwreiv neiateypdv elahmyidna tmqlikdpsq
      241 fdvllcsnlf gdilsdecam itgsmgmlps aslneqgfgl yepaggsapd iagknianpi
      301 aqilslalll rysldaddaa saierainra leegirtgdl argaaavstd emgdiiaryv
      361 aegv