Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_011069243 364 aa linear BCT 19-JUN-2019 ACCESSION WP_011069243 VERSION WP_011069243.1 KEYWORDS RefSeq. SOURCE Shigella flexneri ORGANISM Shigella flexneri Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 364) AUTHORS Dean,A.M. and Golding,G.B. TITLE Protein engineering reveals ancient adaptive replacements in isocitrate dehydrogenase JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3104-3109 (1997) PUBMED 9096353 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: TIGR00169.1 Evidence Source :: JCVI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..364 /organism="Shigella flexneri" /db_xref="taxon:623" gene 1..364 /gene="leuB" Protein 1..364 /product="3-isopropylmalate dehydrogenase" /EC_number="1.1.1.85" /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase activity [Evidence IEA]" /GO_process="GO:0009098 - leucine biosynthetic process [Evidence IEA]" /calculated_mol_wt=39515 Region 4..363 /region_name="PRK00772" /note="3-isopropylmalate dehydrogenase; Provisional" /db_xref="CDD:234832" ORIGIN 1 mmsknyhiav lpgdgigpev mtqalkvlna vrnrfamrit tshydvggaa idnhgqplpp 61 atvegceqad avlfgsvggp kwehlppdqq pergallplr khfklfsnlr paklyqglea 121 fcplradiaa ngfdiqcvre ltggiyfgqp kgregsgqye kafdtevyhr feieriaria 181 fesarkrrhk vtsidkanvl qssilwreiv neiateypdv elahmyidna tmqlikdpsq 241 fdvllcsnlf gdilsdecam itgsmgmlps aslneqgfgl yepaggsapd iagknianpi 301 aqilslalll rysldaddaa saierainra leegirtgdl argaaavstd emgdiiaryv 361 aegv