bifunctional tRNA pseudouridine(32) synthase/23S rRNA

LOCUS       WP_011069242             228 aa            linear   BCT 25-APR-2022
            pseudouridine(746) synthase RluA [Shigella flexneri].
ACCESSION   WP_011069242
VERSION     WP_011069242.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007543.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10158
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..228
                     /gene="rluA"
     Protein         1..228
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /calculated_mol_wt=25552
     Region          20..207
                     /region_name="PseudoU_synth"
                     /note="Pseudouridine synthases catalyze the isomerization
                     of specific uridines in an RNA molecule to pseudouridines
                     (5-ribosyluracil, psi); cl00130"
                     /db_xref="CDD:469624"
     Site            order(80..83,184)
                     /site_type="active"
                     /db_xref="CDD:211346"
ORIGIN      
        1 masgcpafdr cnasvtepkm gmenynppqe pwlvilyqdd himvvnkpsg llsvpgrlee
       61 hkdsvmtriq rdypqaesvh rldmatsgvi vvaltkaaer elkrqfrere pkkqyvarvw
      121 ghpspaeglv dlplicdwpn rpkqkvcyet gkpaqteyev veyaadntar vvlkpitgrs
      181 hqlrvhmlal ghpilgdrfy aspearadgt afvatcrdvd dypsgvwq