4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Listeria

LOCUS       WP_010990127             331 aa            linear   BCT 01-JUN-2019
            monocytogenes].
ACCESSION   WP_010990127
VERSION     WP_010990127.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002187.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK01045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..331
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=36369
     Region          1..294
                     /region_name="ispH"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; PRK01045"
                     /db_xref="CDD:234893"
     Site            order(12,103,198)
                     /site_type="other"
                     /note="Fe-S cluster binding site [ion binding]"
                     /db_xref="CDD:260116"
     Site            order(15,42..43,80..81,131,133,170..171,225..228,271)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:260116"
     Site            order(131,133,226,228)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
ORIGIN      
        1 meiikisprg ycygvidamv iaknasldpn lprpihilgm ivhnkhvtda fesigiytvd
       61 ganreeildk ittgtvifta hgvspsvkak avakglttid atcpdvlhty nlilekqaag
      121 yeiiyigkkg hpepegaygt apdvvhlvet kadidalsll sdkifvtnqt tmskwdvadl
      181 mhyikgkfpk aiqhqeicma tqvrqeaval qakdadltiv vgdprsnnta rlaqvsieka
      241 gtkayriadi teldiewikd akkvavtaga stptqlvrev llfleqfdaa dkttwkrehn
      301 qdferilpkt knkymaekrs qrlahlkngg s