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multidrug efflux MFS transporter MdrL [Listeria monocytogenes].


LOCUS       WP_010990115             397 aa            linear   BCT 11-APR-2024
ACCESSION   WP_010990115
VERSION     WP_010990115.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 397)
  AUTHORS   Romanova,N.A., Wolffs,P.F., Brovko,L.Y. and Griffiths,M.W.
  TITLE     Role of efflux pumps in adaptation and resistance of Listeria
            monocytogenes to benzalkonium chloride
  JOURNAL   Appl. Environ. Microbiol. 72 (5), 3498-3503 (2006)
   PUBMED   16672496
REFERENCE   2  (residues 1 to 397)
  AUTHORS   Mata,M.T., Baquero,F. and Perez-Diaz,J.C.
  TITLE     A multidrug efflux transporter in Listeria monocytogenes
  JOURNAL   FEMS Microbiol. Lett. 187 (2), 185-188 (2000)
   PUBMED   10856655
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to
            BAM10945.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007177
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..397
                     /gene="mdrL"
     Protein         1..397
                     /product="multidrug efflux MFS transporter MdrL"
                     /calculated_mol_wt=42595
     Region          11..379
                     /region_name="MFS_YfmO_like"
                     /note="Bacillus subtilis multidrug efflux protein YfmO and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17474"
                     /db_xref="CDD:341027"
     Site            order(21..22,25..26,29,61,111..112,114..116,119,137,
                     140..141,144,218,221..222,225..227,230,254,258,308..309,
                     313,317,332,335..336,339..340,343)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341027"
ORIGIN      
        1 mmtdkemntg kwitaaasll afmgigvvdp llpsiaesig ashsqvemlf tayiftmaim
       61 mipigivagk mgdkklivig lfivtifall cglsdtigal sifragwgfg nsmfmatamt
      121 mlialsetpg haigiyeasm glgmafgpll ggilgniswr ypffatacli fiafllilfk
      181 vkepkkvapa pteknevaik qmlhlfkyrp flqiafsgmf yyycfftila ysplvlglsa
      241 iqigfvffaw glclalgsak vshaleirfn skqilkgsll acavilallg fidntavdig
      301 livisglilg innalftttv mehspyarsv tsgaynfvrw lgaafaplcs gllsealgmk
      361 mpfivasiic lagmgllfik lkpahftlqq stsikse