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type 2 isopentenyl-diphosphate Delta-isomerase [Listeria


LOCUS       WP_010990109             358 aa            linear   BCT 03-JUN-2024
            monocytogenes].
ACCESSION   WP_010990109
VERSION     WP_010990109.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 358)
  AUTHORS   Janczak,M.W. and Poulter,C.D.
  TITLE     Kinetic and Binding Studies of Streptococcus pneumoniae Type 2
            Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase
  JOURNAL   Biochemistry 55 (15), 2260-2268 (2016)
   PUBMED   27003727
REFERENCE   2  (residues 1 to 358)
  AUTHORS   Dutoit,R., de Ruyck,J., Durisotti,V., Legrain,C., Jacobs,E. and
            Wouters,J.
  TITLE     Overexpression, physicochemical characterization, and modeling of a
            hyperthermophilic pyrococcus furiosus type 2 IPP isomerase
  JOURNAL   Proteins 71 (4), 1699-1707 (2008)
   PUBMED   18076031
REFERENCE   3  (residues 1 to 358)
  AUTHORS   Takagi,M., Kaneda,K., Shimizu,T., Hayakawa,Y., Seto,H. and
            Kuzuyama,T.
  TITLE     Bacillus subtilis ypgA gene is fni, a nonessential gene encoding
            type 2 isopentenyl diphosphate isomerase
  JOURNAL   Biosci Biotechnol Biochem 68 (1), 132-137 (2004)
   PUBMED   14745175
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02151.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..358
                     /gene="fni"
     Protein         1..358
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39359
     Region          11..338
                     /region_name="IPP_isom_2"
                     /note="isopentenyl-diphosphate delta-isomerase, type 2;
                     TIGR02151"
                     /db_xref="CDD:273999"
     Site            order(38..41,44,154,191,194..195,199,243,251,272..273,309,
                     312)
                     /site_type="other"
                     /note="homotetramer interface [polypeptide binding]"
                     /db_xref="CDD:239205"
     Site            order(70..73,99,128,153,190,265..267,289)
                     /site_type="other"
                     /note="FMN binding site [chemical binding]"
                     /db_xref="CDD:239205"
     Site            order(72,79..80)
                     /site_type="other"
                     /note="homodimer contacts [polypeptide binding]"
                     /db_xref="CDD:239205"
     Site            order(99,128,153,190,265,288..289)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:239205"
     Site            order(128,130,153)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:239205"
ORIGIN      
        1 mqknddllre rrkdehvalg vkqneqlaps slkdiqligt siprynvkdi dltttifgkn
       61 vpfpfyinam tggsrhtkki naelaeiare vaipmavgsq saalknssli dtynivrein
      121 pngmilanvs pevaiqdglq aiemleanal qihinpaqel vmqegdrsfs hwltrieeyv
      181 klspvpivvk evgfgmtret vktladigvq tvdlagkggt nfaqiendrr rdqaydflld
      241 wgistgqali dmqhqdapki aylasggirn pldiikalal gadsvgmagq iiyslkkegv
      301 tktieklelw keqlrglfvl anakniaelk ttplivsgel akwgtlrein lvklanrk