Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

rhomboid family protein [Listeria monocytogenes].


LOCUS       WP_010990098             512 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_010990098
VERSION     WP_010990098.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 512)
  AUTHORS   Rawlings,N.D., Barrett,A.J. and Finn,R.
  TITLE     Twenty years of the MEROPS database of proteolytic enzymes, their
            substrates and inhibitors
  JOURNAL   Nucleic Acids Res 44 (D1), D343-D350 (2016)
   PUBMED   26527717
REFERENCE   2  (residues 1 to 512)
  AUTHORS   Brooks,C.L. and Lemieux,M.J.
  TITLE     Untangling structure-function relationships in the rhomboid family
            of intramembrane proteases
  JOURNAL   Biochim Biophys Acta 1828 (12), 2862-2872 (2013)
   PUBMED   24099005
REFERENCE   3  (residues 1 to 512)
  AUTHORS   Urban,S. and Dickey,S.W.
  TITLE     The rhomboid protease family: a decade of progress on function and
            mechanism
  JOURNAL   Genome Biol 12 (10), 231 (2011)
   PUBMED   22035660
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 512)
  AUTHORS   Koonin,E.V., Makarova,K.S., Rogozin,I.B., Davidovic,L.,
            Letellier,M.C. and Pellegrini,L.
  TITLE     The rhomboids: a nearly ubiquitous family of intramembrane serine
            proteases that probably evolved by multiple ancient horizontal gene
            transfers
  JOURNAL   Genome Biol 4 (3), R19 (2003)
   PUBMED   12620104
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10483871
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..512
                     /product="rhomboid family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /calculated_mol_wt=57927
     Region          180..363
                     /region_name="GlpG"
                     /note="Membrane-associated serine protease, rhomboid
                     family [Posttranslational modification, protein turnover,
                     chaperones]; COG0705"
                     /db_xref="CDD:440469"
     Region          <407..510
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          430..460
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
ORIGIN      
        1 msfqeqyvfw rltnyflgve kyrlihlhee kqelwlents qkkrpviriq mkelswanvv
       61 erdvthtlhv tenlrkqmgr lklplvniyi tpfepmgdis pffgqsiasp nekvklenil
      121 laneqmrehl diliktlelp eeafvlpnei tkelvakere qviayittkv neeqkvarns
      181 kpivtytfig llvaaflwls fqggttnsfn likwggkfnp liyagewwrf ispiflhsgl
      241 mhiasnavml yivgawaeri ygkwryvlil llggicgnia sfalnmnlsv gastavfavm
      301 gallylvvlk pnlyaktigv siaslvainl lidvfssqid iaghigglvg gfllagalsl
      361 pkqffhwrrl aygislfava vlflyfgyqk geqpydpmqa nvavqqylqe qnkkeatkit
      421 dnlissgsad gysytyaasi alqdkqidka etmakeaini dkdipeahyy lsvcyrikgd
      481 mpnaikeans arelssnpff dsyydeleki ke